Transcription shapes 3D chromatin organization by interacting with loop extrusion

Cohesin folds mammalian interphase chromosomes by extruding the chromatin fiber into numerous loops. “Loop extrusion” can be impeded by chromatin-bound factors, such as CTCF, which generates characteristic and functional chromatin organization patterns. It has been proposed that transcription reloca...

Descripción completa

Detalles Bibliográficos
Autores principales: Banigan, Edward J., Tang, Wen, van den Berg, Aafke A., Stocsits, Roman R., Wutz, Gordana, Brandão, Hugo B., Busslinger, Georg A., Peters, Jan-Michael, Mirny, Leonid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089175/
https://www.ncbi.nlm.nih.gov/pubmed/36897969
http://dx.doi.org/10.1073/pnas.2210480120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089175/
https://www.ncbi.nlm.nih.gov/pubmed/36897969
http://dx.doi.org/10.1073/pnas.2210480120

Ejemplares similares