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Mechanistic analysis of a novel membrane-interacting variable loop in the pleckstrin-homology domain critical for dynamin function

Classical dynamins are best understood for their ability to generate vesicles by membrane fission. During clathrin-mediated endocytosis (CME), dynamin is recruited to the membrane through multivalent protein and lipid interactions between its proline-rich domain (PRD) with SRC Homology 3 (SH3) domai...

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Detalles Bibliográficos
Autores principales: Khurana, Himani, Baratam, Krishnakanth, Bhattacharyya, Soumya, Srivastava, Anand, Pucadyil, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089193/
https://www.ncbi.nlm.nih.gov/pubmed/36888655
http://dx.doi.org/10.1073/pnas.2215250120

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