KMT2D acetylation by CREBBP reveals a cooperative functional interaction at enhancers in normal and malignant germinal center B cells

Heterozygous inactivating mutations of the KMT2D methyltransferase and the CREBBP acetyltransferase are among the most common genetic alterations in B cell lymphoma and co-occur in 40 to 60% of follicular lymphoma (FL) and 30% of EZB/C3 diffuse large B cell lymphoma (DLBCL) cases, suggesting they ma...

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Detalles Bibliográficos
Autores principales: Vlasevska, Sofija, Garcia-Ibanez, Laura, Duval, Romain, Holmes, Antony B., Jahan, Rahat, Cai, Bowen, Kim, Andrew, Mo, Tongwei, Basso, Katia, Soni, Rajesh K., Bhagat, Govind, Dalla-Favera, Riccardo, Pasqualucci, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089214/
https://www.ncbi.nlm.nih.gov/pubmed/36893259
http://dx.doi.org/10.1073/pnas.2218330120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089214/
https://www.ncbi.nlm.nih.gov/pubmed/36893259
http://dx.doi.org/10.1073/pnas.2218330120

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