Design, synthesis, and characterization of protein origami based on self-assembly of a brick and staple artificial protein pair

A versatile strategy to create an inducible protein assembly with predefined geometry is demonstrated. The assembly is triggered by a binding protein that staples two identical protein bricks together in a predictable spatial conformation. The brick and staple proteins are designed for mutual direct...

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Detalles Bibliográficos
Autores principales: Moreaud, Laureen, Viollet, Sébastien, Urvoas, Agathe, Valerio-Lepiniec, Marie, Mesneau, Agnès, Li de la Sierra-Gallay, Inès, Miller, Jessalyn, Ouldali, Malika, Marcelot, Cécile, Balor, Stéphanie, Soldan, Vanessa, Meriadec, Cristelle, Artzner, Franck, Dujardin, Erik, Minard, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089216/
https://www.ncbi.nlm.nih.gov/pubmed/36893280
http://dx.doi.org/10.1073/pnas.2218428120

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