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Increased flexibility of the SARS-CoV-2 RNA-binding site causes resistance to remdesivir
Mutations continue to accumulate within the SARS-CoV-2 genome, and the ongoing epidemic has shown no signs of ending. It is critical to predict problematic mutations that may arise in clinical environments and assess their properties in advance to quickly implement countermeasures against future var...
Autores principales: | Torii, Shiho, Kim, Kwang Su, Koseki, Jun, Suzuki, Rigel, Iwanami, Shoya, Fujita, Yasuhisa, Jeong, Yong Dam, Ito, Jumpei, Asakura, Hiroyuki, Nagashima, Mami, Sadamasu, Kenji, Yoshimura, Kazuhisa, Sato, Kei, Matsuura, Yoshiharu, Shimamura, Teppei, Iwami, Shingo, Fukuhara, Takasuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089321/ https://www.ncbi.nlm.nih.gov/pubmed/36972312 http://dx.doi.org/10.1371/journal.ppat.1011231 |
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