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Increased flexibility of the SARS-CoV-2 RNA-binding site causes resistance to remdesivir

Mutations continue to accumulate within the SARS-CoV-2 genome, and the ongoing epidemic has shown no signs of ending. It is critical to predict problematic mutations that may arise in clinical environments and assess their properties in advance to quickly implement countermeasures against future var...

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Detalles Bibliográficos
Autores principales: Torii, Shiho, Kim, Kwang Su, Koseki, Jun, Suzuki, Rigel, Iwanami, Shoya, Fujita, Yasuhisa, Jeong, Yong Dam, Ito, Jumpei, Asakura, Hiroyuki, Nagashima, Mami, Sadamasu, Kenji, Yoshimura, Kazuhisa, Sato, Kei, Matsuura, Yoshiharu, Shimamura, Teppei, Iwami, Shingo, Fukuhara, Takasuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089321/
https://www.ncbi.nlm.nih.gov/pubmed/36972312
http://dx.doi.org/10.1371/journal.ppat.1011231

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