Network models of protein phosphorylation, acetylation, and ubiquitination connect metabolic and cell signaling pathways in lung cancer

We analyzed large-scale post-translational modification (PTM) data to outline cell signaling pathways affected by tyrosine kinase inhibitors (TKIs) in ten lung cancer cell lines. Tyrosine phosphorylated, lysine ubiquitinated, and lysine acetylated proteins were concomitantly identified using sequent...

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Detalles Bibliográficos
Autores principales: Ross, Karen E., Zhang, Guolin, Akcora, Cuneyt, Lin, Yu, Fang, Bin, Koomen, John, Haura, Eric B., Grimes, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089347/
https://www.ncbi.nlm.nih.gov/pubmed/36996232
http://dx.doi.org/10.1371/journal.pcbi.1010690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089347/
https://www.ncbi.nlm.nih.gov/pubmed/36996232
http://dx.doi.org/10.1371/journal.pcbi.1010690

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