Cargando…

Human Umbilical Cord Mesenchymal Stem Cells Inhibit Pyroptosis of Renal Tubular Epithelial Cells through miR-342-3p/Caspase1 Signaling Pathway in Diabetic Nephropathy

Diabetic nephropathy (DN) is one of the microvascular complications of diabetes. Recent studies suggest that the pyroptosis of renal tubular epithelial cell plays a critical role in DN. Currently, effective therapeutic strategies to counteract and reverse the progression of DN are lacking. Mesenchym...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Shuo, Zhang, Ke, Zhang, Yaqi, He, Jing, Ouyang, Yu, Lang, Ruibo, Ao, Chunchun, Jiang, Yijia, Xiao, Huan, Li, Yu, Li, Mao, Li, Changyong, Wu, Dongcheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089783/ https://www.ncbi.nlm.nih.gov/pubmed/37056456 http://dx.doi.org/10.1155/2023/5584894

Ejemplares similares

Human umbilical cord mesenchymal stem cells ameliorate acute liver failure by inhibiting apoptosis, inflammation and pyroptosis
por: Liu, Mengting, et al.
Publicado: (2021)

MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against diabetic nephropathy in rats through facilitating M2 macrophage polarization
por: Zhang, Yaqi, et al.
Publicado: (2022)

Human umbilical cord-derived mesenchymal stem cells prevent the progression of early diabetic nephropathy through inhibiting inflammation and fibrosis
por: Xiang, E, et al.
Publicado: (2020)

Umbilical Cord-Derived Mesenchymal Stem Cells Ameliorate Nephrocyte Injury and Proteinuria in a Diabetic Nephropathy Rat Model
por: Chen, Lian, et al.
Publicado: (2020)

Caspase-11-mediated tubular epithelial pyroptosis underlies contrast-induced acute kidney injury
por: Zhang, Zhen, et al.
Publicado: (2018)

Alpha‐kinase1 promotes tubular injury and interstitial inflammation in diabetic nephropathy by canonical pyroptosis pathway
por: Cui, Xinyuan, et al.
Publicado: (2023)

The role of discoid domain receptor 1 on renal tubular epithelial pyroptosis in diabetic nephropathy
por: Zhao, Weichen, et al.
Publicado: (2022)

Overexpression of aquaporin 2 in renal tubular epithelial cells alleviates pyroptosis
por: Fan, Yu, et al.
Publicado: (2021)

Luteolin induces pyroptosis in HT-29 cells by activating the Caspase1/Gasdermin D signalling pathway
por: Chen, Yiliu, et al.
Publicado: (2022)

Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells
por: Yu, Junhui, et al.
Publicado: (2019)

miRNA-342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6
por: Jiang, Zhen-Huan, et al.
Publicado: (2020)

Shen-Ling-Bai-Zhu-San Improves Dextran Sodium Sulfate-Induced Colitis by Inhibiting Caspase-1/Caspase-11-Mediated Pyroptosis
por: Chao, Limin, et al.
Publicado: (2020)

Induction of Pyroptosis in Renal Tubular Epithelial Cells Using High Glucose
por: Liu, Yinghong, et al.
Publicado: (2022)

Balance Cell Apoptosis and Pyroptosis of Caspase-3-Activating Chemotherapy for Better Antitumor Therapy
por: Li, Lingjiao, et al.
Publicado: (2022)

Caspase-mediated LPS sensing and pyroptosis signaling in Hydra
por: Chen, Shouwen, et al.
Publicado: (2023)

The Role of Caspase-11 and Pyroptosis in the Regulation of Inflammation in Peri-Implantitis
por: Jiao, Pengcheng, et al.
Publicado: (2023)

Caspase-11-dependent pyroptosis of lung epithelial cells protects from melioidosis while caspase-1 mediates macrophage pyroptosis and production of IL-18
por: Wang, Jinyong, et al.
Publicado: (2018)

Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway
por: Ding, Baozhu, et al.
Publicado: (2021)

Duck gasdermin E is a substrate of caspase-3/-7 and an executioner of pyroptosis
por: Li, Hanqing, et al.
Publicado: (2023)

Triclabendazole Induces Pyroptosis by Activating Caspase-3 to Cleave GSDME in Breast Cancer Cells
por: Yan, Liang, et al.
Publicado: (2021)

Circ_0004951 Promotes Pyroptosis of Renal Tubular Cells via the NLRP3 Inflammasome in Diabetic Kidney Disease
por: Wang, Yulin, et al.
Publicado: (2022)

TNF-α contributes to sarcopenia through caspase-8/caspase-3/GSDME-mediated pyroptosis
por: Wu, Jingying, et al.
Publicado: (2023)

Scutellarin inhibits caspase-11 activation and pyroptosis in macrophages via regulating PKA signaling
por: Ye, Jiezhou, et al.
Publicado: (2021)

DUSP2-mediated inhibition of tubular epithelial cell pyroptosis confers nephroprotection in acute kidney injury
por: Xiong, Jiachuan, et al.
Publicado: (2022)

Corrigendum to “Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway”
por: Ding, Baozhu, et al.
Publicado: (2022)

Secoisolariciresinol diglucoside induces pyroptosis by activating caspase‐1 to cleave GSDMD in colorectal cancer cells
por: Chen, Tuo, et al.
Publicado: (2022)

ASC/inflammasome-independent pyroptosis in ovarian cancer cells through translational augmentation of caspase-1
por: Calbay, Ozlem, et al.
Publicado: (2023)

Mini-Review: GSDME-Mediated Pyroptosis in Diabetic Nephropathy
por: Li, Wen, et al.
Publicado: (2021)

GSDME-dependent pyroptosis signaling pathway in diabetic nephropathy
por: Li, Shengyu, et al.
Publicado: (2023)

Heme oxygenase‑1 inhibits renal tubular epithelial cell pyroptosis by regulating mitochondrial function through PINK1
por: Li, Hai-Bo, et al.
Publicado: (2023)

Focus on the Mechanisms and Functions of Pyroptosis, Inflammasomes, and Inflammatory Caspases in Infectious Diseases
por: Song, Haichao, et al.
Publicado: (2022)

GSDMEa-mediated pyroptosis is bi-directionally regulated by caspase and required for effective bacterial clearance in teleost
por: Xu, Hang, et al.
Publicado: (2022)

Caspase-1 interdomain linker cleavage is required for pyroptosis
por: Ball, Daniel P, et al.
Publicado: (2020)

Inflammatory Caspases Drive Pyroptosis in Acute Lung Injury
por: Liu, Bohao, et al.
Publicado: (2021)

Blocking GSDME-mediated pyroptosis in renal tubular epithelial cells alleviates disease activity in lupus mice
por: Luo, Guihu, et al.
Publicado: (2022)

Identification of pyroptosis-related genes and potential drugs in diabetic nephropathy
por: Yan, Meng, et al.
Publicado: (2023)

Ophiopogonin B alleviates cisplatin resistance of lung cancer cells by inducing Caspase-1/GSDMD dependent pyroptosis
por: Cheng, Ziyu, et al.
Publicado: (2022)

Downregulation of renal tubular Wnt/β-catenin signaling by Dickkopf-3 induces tubular cell death in proteinuric nephropathy
por: Wong, D W L, et al.
Publicado: (2016)

Nephropathy Is Aggravated by Fatty Acids in Diabetic Kidney Disease through Tubular Epithelial Cell Necroptosis and Is Alleviated by an RIPK-1 Inhibitor
por: Yu, Qi, et al.
Publicado: (2023)

Caspase-1-Dependent Pyroptosis of Peripheral Blood Mononuclear Cells Is Associated with the Severity and Mortality of Septic Patients
por: Wang, Yuchang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_jfaguso3fs0skkd155voapoqq8