Cargando…

YTHDC2-mediated m6A mRNA modification of Id3 suppresses cisplatin resistance in non-small cell lung cancer

BACKGROUND: The methylation of adenosines at the N6 position (N6-methyladenosine; m6A) is one of the most conserved internal RNA modifications. m6A can modulate the expression of oncogenes or tumor suppressor genes, as well as m6A levels and the expression and activity of m6A enzymes, thus influenci...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xifan, Hu, Yu’an, Li, Xiaoqing, Zhu, Chuandong, Chen, Fangfang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089841/ https://www.ncbi.nlm.nih.gov/pubmed/37065597 http://dx.doi.org/10.21037/jtd-23-187

Ejemplares similares

m(6)A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2
por: Mao, Yuanhui, et al.
Publicado: (2019)

The m6A RNA Modification Quantity and the Prognostic Effect of Reader YTHDC2 in Colorectal Cancer
por: Liu, Tianyu, et al.
Publicado: (2022)

The m6A reader YTHDC1-mediated lncRNA CTBP1-AS2 m6A modification accelerates cholangiocarcinoma progression
por: Jin, Zhe, et al.
Publicado: (2023)

Overexpression of m6A-factors METTL3, ALKBH5, and YTHDC1 alters HPV16 mRNA splicing
por: Cui, Xiaoxu, et al.
Publicado: (2022)

YTHDC1 mediates nuclear export of N(6)-methyladenosine methylated mRNAs
por: Roundtree, Ian A, et al.
Publicado: (2017)

METTL3-mediated m(6)A mRNA modification of FBXW7 suppresses lung adenocarcinoma
por: Wu, Yingtong, et al.
Publicado: (2021)

Structural effects of m(6)A modification of the Xist A-repeat AUCG tetraloop and its recognition by YTHDC1
por: Jones, Alisha N, et al.
Publicado: (2022)

KIAA1429 regulates the migration and invasion of hepatocellular carcinoma by altering m6A modification of ID2 mRNA
por: Cheng, Xiaoyu, et al.
Publicado: (2019)

Nuclear m6A reader YTHDC1 promotes muscle stem cell activation/proliferation by regulating mRNA splicing and nuclear export
por: Qiao, Yulong, et al.
Publicado: (2023)

YTHDC1 mitigates ischemic stroke by promoting Akt phosphorylation through destabilizing PTEN mRNA
por: Zhang, Zhaolong, et al.
Publicado: (2020)

The m(6)A reader YTHDC2 inhibits lung adenocarcinoma tumorigenesis by suppressing SLC7A11-dependent antioxidant function
por: Ma, Lifang, et al.
Publicado: (2020)

YTHDC2 control of gametogenesis requires helicase activity but not m(6)A binding
por: Saito, Yuhki, et al.
Publicado: (2022)

Roles and mechanisms of the m(6)A reader YTHDC1 in biological processes and diseases
por: Yan, Huaqing, et al.
Publicado: (2022)

Downregulation of m(6)A reader YTHDC2 promotes tumor progression and predicts poor prognosis in non‐small cell lung cancer
por: Sun, Shulei, et al.
Publicado: (2020)

The N6-methyladenosine reader protein YTHDC2 promotes gastric cancer progression via enhancing YAP mRNA translation
por: Yuan, Wei, et al.
Publicado: (2021)

YTHDC2 inhibits rat bone mesenchymal stem cells osteogenic differentiation by accelerating RUNX2 mRNA degradation via m6A methylation
por: Ma, Bo, et al.
Publicado: (2023)

The Effect of N6-Methyladenosine Regulators and m6A Reader YTHDC1-Mediated N6-Methyladenosine Modification Is Involved in Oxidative Stress in Human Aortic Dissection
por: Yin, Fanxing, et al.
Publicado: (2023)

The m(6)A reader protein YTHDC2 interacts with the small ribosomal subunit and the 5′–3′ exoribonuclease XRN1
por: Kretschmer, Jens, et al.
Publicado: (2018)

YTHDC2-Mediated circYTHDC2 N6-Methyladenosine Modification Promotes Vascular Smooth Muscle Cells Dysfunction Through Inhibiting Ten-Eleven Translocation 2
por: Yuan, Jun, et al.
Publicado: (2021)

Pathogenic variants in the human m(6)A reader YTHDC2 are associated with primary ovarian insufficiency
por: McGlacken-Byrne, Sinéad M., et al.
Publicado: (2022)

m(6)A reader YTHDC1 modulates autophagy by targeting SQSTM1 in diabetic skin
por: Liang, Diefei, et al.
Publicado: (2021)

METTL3-mediated m6A modification of Bcl-2 mRNA promotes non-small cell lung cancer progression
por: Zhang, Yongxi, et al.
Publicado: (2021)

The m(6)A reader YTHDC2 is essential for escape from KSHV SOX-induced RNA decay
por: Macveigh-Fierro, Daniel, et al.
Publicado: (2022)

Depletion of m(6)A reader protein YTHDC1 induces dilated cardiomyopathy by abnormal splicing of Titin
por: Gao, Siyun, et al.
Publicado: (2021)

m(6)A modification suppresses ocular melanoma through modulating HINT2 mRNA translation
por: Jia, Ruobing, et al.
Publicado: (2019)

Dynamic regulation and functions of mRNA m6A modification
por: Wang, Shanshan, et al.
Publicado: (2022)

Modulation of translational decoding by m(6)A modification of mRNA
por: Jain, Sakshi, et al.
Publicado: (2023)

[Corrigendum] METTL3‑mediated m6A modification of Bcl‑2 mRNA promotes non‑small cell lung cancer progression
por: Zhang, Yongxi, et al.
Publicado: (2023)

The RNA m6A-Binding Protein YTHDC1 Is Downregulated and Associated With M2 Macrophage Infiltration in Muscle-Invasive Bladder Cancer
por: Zhao, Lamei, et al.
Publicado: (2023)

Analysis of mRNA m(6)A modification and mRNA expression profiles in middle ear cholesteatoma
por: Xie, Shumin, et al.
Publicado: (2023)

Nuclear m(6)A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development
por: Kasowitz, Seth D., et al.
Publicado: (2018)

PLAA suppresses ovarian cancer metastasis via METTL3-mediated m(6)A modification of TRPC3 mRNA
por: Shen, Zhangjin, et al.
Publicado: (2022)

m(6)A modification of lncRNA PCAT6 promotes bone metastasis in prostate cancer through IGF2BP2‐mediated IGF1R mRNA stabilization
por: Lang, Chuandong, et al.
Publicado: (2021)

The m6A reader YTHDC1 regulates muscle stem cell proliferation via PI4K–Akt–mTOR signalling
por: Liu, Jin, et al.
Publicado: (2023)

Aberrant Regulation of mRNA m(6)A Modification in Cancer Development
por: Luo, Junyun, et al.
Publicado: (2018)

Diverse molecular functions of m(6)A mRNA modification in cancer
por: Han, Seung Hun, et al.
Publicado: (2020)

Downregulation of m(6)A Reader YTHDC2 Promotes the Proliferation and Migration of Malignant Lung Cells via CYLD/NF-κB Pathway
por: Wang, Jin, et al.
Publicado: (2021)

Multiple Phosphorylations of SR Protein SRSF3 and Its Binding to m(6)A Reader YTHDC1 in Human Cells
por: Tatsuno, Takanori, et al.
Publicado: (2022)

The m(6)A reader YTHDC1 and the RNA helicase DDX5 control the production of rhabdomyosarcoma-enriched circRNAs
por: Dattilo, Dario, et al.
Publicado: (2023)

New mRNA modification?
por: Leslie, Mitch
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_c29okih0i4v3ni220siekb2rrm