Intact regulation of G1/S transition renders esophageal squamous cell carcinoma sensitive to PI3Kα inhibitors

Phosphatidylinositol 3-kinase alpha (PI3Kα) inhibitors are currently evaluated for the therapy of esophageal squamous cell carcinoma (ESCC). It is of great importance to identify potential biomarkers to predict or monitor the efficacy of PI3Kα inhibitors in an aim to improve the clinical responsive...

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Detalles Bibliográficos
Autores principales: Zhang, Xu, Wang, Yuxiang, Zhang, Xi, Shen, Yanyan, Yang, Kang, Ma, Qingyang, Qiao, Yuemei, Shi, Jiajie, Wang, Yi, Xu, Lan, Yang, Biyu, Ge, Gaoxiang, Hu, Landian, Kong, Xiangyin, Yang, Chunhao, Chen, Yi, Ding, Jian, Meng, Linghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090078/
https://www.ncbi.nlm.nih.gov/pubmed/37041169
http://dx.doi.org/10.1038/s41392-023-01359-x

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