Lung-specific MCEMP1 functions as an adaptor for KIT to promote SCF-mediated mast cell proliferation

Lung mast cells are important in host defense, and excessive proliferation or activation of these cells can cause chronic inflammatory disorders like asthma. Two parallel pathways induced by KIT–stem cell factor (SCF) and FcεRI–immunoglobulin E interactions are critical for the proliferation and act...

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Detalles Bibliográficos
Autores principales: Choi, Youn Jung, Yoo, Ji-Seung, Jung, Kyle, Rice, Logan, Kim, Dokyun, Zlojutro, Violetta, Frimel, Matthew, Madden, Evan, Choi, Un Yung, Foo, Suan-Sin, Choi, Younho, Jiang, Zhongyi, Johnson, Holly, Kwak, Mi-Jeong, Kang, Seokmin, Hong, Brian, Seo, Gil Ju, Kim, Stephanie, Lee, Shin-Ae, Amini-Bavil-Olyaee, Samad, Maazi, Hadi, Akbari, Omid, Asosingh, Kewal, Jung, Jae U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090139/
https://www.ncbi.nlm.nih.gov/pubmed/37041174
http://dx.doi.org/10.1038/s41467-023-37873-3

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