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Challenges and opportunities in analyzing and modeling peptide presentation by HLA-II proteins

The human leukocyte antigen (HLA) proteins are an indispensable component of adaptive immunity because of their role in presenting self and foreign peptides to T cells. Further, many complex diseases are associated with genetic variation in the HLA region, implying an important role for specific HLA...

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Detalles Bibliográficos
Autores principales: ElAbd, Hesham, Bacher, Petra, Tholey, Andreas, Lenz, Tobias L., Franke, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090296/
https://www.ncbi.nlm.nih.gov/pubmed/37063883
http://dx.doi.org/10.3389/fimmu.2023.1107266