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Challenges and opportunities in analyzing and modeling peptide presentation by HLA-II proteins
The human leukocyte antigen (HLA) proteins are an indispensable component of adaptive immunity because of their role in presenting self and foreign peptides to T cells. Further, many complex diseases are associated with genetic variation in the HLA region, implying an important role for specific HLA...
Autores principales: | ElAbd, Hesham, Bacher, Petra, Tholey, Andreas, Lenz, Tobias L., Franke, Andre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090296/ https://www.ncbi.nlm.nih.gov/pubmed/37063883 http://dx.doi.org/10.3389/fimmu.2023.1107266 |
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