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Genetic engineering strategies to enhance antitumor reactivity and reduce alloreactivity for allogeneic cell-based cancer therapy

The realm of cell-based immunotherapy holds untapped potential for the development of next-generation cancer treatment through genetic engineering of chimeric antigen receptor (CAR)-engineered T (CAR-T) cell therapies for targeted eradication of cancerous malignancies. Such allogeneic “off-the-shelf...

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Detalles Bibliográficos
Autores principales:	Chen, Yuning, Zhu, Yichen, Kramer, Adam, Fang, Ying, Wilson, Matthew, Li, Yan-Ruide, Yang, Lili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090359/ https://www.ncbi.nlm.nih.gov/pubmed/37064017 http://dx.doi.org/10.3389/fmed.2023.1135468

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