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Primary intestinal type mucinous adenocarcinoma of the ovary diagnosed during pregnancy – Maternal and neonatal treatment and outcomes: A case report

The incidence of ovarian cancer during pregnancy is low. Most adnexal tumors removed during pregnancy are benign, with ovarian carcinomas found in approximately 1: 10,000–1: 50,000 pregnancies. Literature on this disease is scarce and consists mostly of retrospective studies and case reports. We rep...

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Autores principales: Hase, Eliane Azeka, Shinohara, Henrique Norio, Alves Filho, João Alberto Garcia, Sadalla, José Carlos, Ab́saber, Alexandre Muxfeldt, Francisco, Rossana Pulcineli Vieira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090370/
https://www.ncbi.nlm.nih.gov/pubmed/37064023
http://dx.doi.org/10.3389/fmed.2023.1138447
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author Hase, Eliane Azeka
Shinohara, Henrique Norio
Alves Filho, João Alberto Garcia
Sadalla, José Carlos
Ab́saber, Alexandre Muxfeldt
Francisco, Rossana Pulcineli Vieira
author_facet Hase, Eliane Azeka
Shinohara, Henrique Norio
Alves Filho, João Alberto Garcia
Sadalla, José Carlos
Ab́saber, Alexandre Muxfeldt
Francisco, Rossana Pulcineli Vieira
author_sort Hase, Eliane Azeka
collection PubMed
description The incidence of ovarian cancer during pregnancy is low. Most adnexal tumors removed during pregnancy are benign, with ovarian carcinomas found in approximately 1: 10,000–1: 50,000 pregnancies. Literature on this disease is scarce and consists mostly of retrospective studies and case reports. We report the case of a pregnant patient who presented with a primary intestinal-type mucinous adenocarcinoma of the ovary and underwent unilateral salpingo-oophorectomy, with no additional surgical or chemotherapy treatment after the histological diagnosis, despite an infiltrative stromal invasion pattern. To the best of our knowledge, no such case has been previously reported. Conservative treatment in this case of early ovarian carcinoma is possible during pregnancy and should be performed in the Department of Gynecological Oncology and Obstetrics of a tertiary referral hospital. Given the possibility of disease recurrence, such patients require strict clinical oncological surveillance, specialized prenatal care, and assistance from a multidisciplinary team to improve the maternal and perinatal outcomes.
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spelling pubmed-100903702023-04-13 Primary intestinal type mucinous adenocarcinoma of the ovary diagnosed during pregnancy – Maternal and neonatal treatment and outcomes: A case report Hase, Eliane Azeka Shinohara, Henrique Norio Alves Filho, João Alberto Garcia Sadalla, José Carlos Ab́saber, Alexandre Muxfeldt Francisco, Rossana Pulcineli Vieira Front Med (Lausanne) Medicine The incidence of ovarian cancer during pregnancy is low. Most adnexal tumors removed during pregnancy are benign, with ovarian carcinomas found in approximately 1: 10,000–1: 50,000 pregnancies. Literature on this disease is scarce and consists mostly of retrospective studies and case reports. We report the case of a pregnant patient who presented with a primary intestinal-type mucinous adenocarcinoma of the ovary and underwent unilateral salpingo-oophorectomy, with no additional surgical or chemotherapy treatment after the histological diagnosis, despite an infiltrative stromal invasion pattern. To the best of our knowledge, no such case has been previously reported. Conservative treatment in this case of early ovarian carcinoma is possible during pregnancy and should be performed in the Department of Gynecological Oncology and Obstetrics of a tertiary referral hospital. Given the possibility of disease recurrence, such patients require strict clinical oncological surveillance, specialized prenatal care, and assistance from a multidisciplinary team to improve the maternal and perinatal outcomes. Frontiers Media S.A. 2023-03-29 /pmc/articles/PMC10090370/ /pubmed/37064023 http://dx.doi.org/10.3389/fmed.2023.1138447 Text en Copyright © 2023 Hase, Shinohara, Alves Filho, Sadalla, Ab́saber and Francisco. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Hase, Eliane Azeka
Shinohara, Henrique Norio
Alves Filho, João Alberto Garcia
Sadalla, José Carlos
Ab́saber, Alexandre Muxfeldt
Francisco, Rossana Pulcineli Vieira
Primary intestinal type mucinous adenocarcinoma of the ovary diagnosed during pregnancy – Maternal and neonatal treatment and outcomes: A case report
title Primary intestinal type mucinous adenocarcinoma of the ovary diagnosed during pregnancy – Maternal and neonatal treatment and outcomes: A case report
title_full Primary intestinal type mucinous adenocarcinoma of the ovary diagnosed during pregnancy – Maternal and neonatal treatment and outcomes: A case report
title_fullStr Primary intestinal type mucinous adenocarcinoma of the ovary diagnosed during pregnancy – Maternal and neonatal treatment and outcomes: A case report
title_full_unstemmed Primary intestinal type mucinous adenocarcinoma of the ovary diagnosed during pregnancy – Maternal and neonatal treatment and outcomes: A case report
title_short Primary intestinal type mucinous adenocarcinoma of the ovary diagnosed during pregnancy – Maternal and neonatal treatment and outcomes: A case report
title_sort primary intestinal type mucinous adenocarcinoma of the ovary diagnosed during pregnancy – maternal and neonatal treatment and outcomes: a case report
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090370/
https://www.ncbi.nlm.nih.gov/pubmed/37064023
http://dx.doi.org/10.3389/fmed.2023.1138447
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