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Heart-brain axis: Association of congenital heart abnormality and brain diseases
Brain diseases are a major burden on human health worldwide, and little is known about how most brain diseases develop. It is believed that cardiovascular diseases can affect the function of the brain, and many brain diseases are associated with heart dysfunction, which is called the heart-brain axi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090520/ https://www.ncbi.nlm.nih.gov/pubmed/37063948 http://dx.doi.org/10.3389/fcvm.2023.1071820 |
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author | Sha, Leihao Li, Yajiao Zhang, Yunwu Tang, Yusha Li, Baichuan Chen, Yucheng Chen, Lei |
author_facet | Sha, Leihao Li, Yajiao Zhang, Yunwu Tang, Yusha Li, Baichuan Chen, Yucheng Chen, Lei |
author_sort | Sha, Leihao |
collection | PubMed |
description | Brain diseases are a major burden on human health worldwide, and little is known about how most brain diseases develop. It is believed that cardiovascular diseases can affect the function of the brain, and many brain diseases are associated with heart dysfunction, which is called the heart-brain axis. Congenital heart abnormalities with anomalous hemodynamics are common treatable cardiovascular diseases. With the development of cardiovascular surgeries and interventions, the long-term survival of patients with congenital heart abnormalities continues to improve. However, physicians have reported that patients with congenital heart abnormalities have an increased risk of brain diseases in adulthood. To understand the complex association between congenital heart abnormalities and brain diseases, the paper reviews relevant clinical literature. Studies have shown that congenital heart abnormalities are associated with most brain diseases, including stroke, migraine, dementia, infection of the central nervous system, epilepsy, white matter lesions, and affective disorders. However, whether surgeries or other interventions could benefit patients with congenital heart abnormalities and brain diseases remains unclear because of limited evidence. |
format | Online Article Text |
id | pubmed-10090520 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100905202023-04-13 Heart-brain axis: Association of congenital heart abnormality and brain diseases Sha, Leihao Li, Yajiao Zhang, Yunwu Tang, Yusha Li, Baichuan Chen, Yucheng Chen, Lei Front Cardiovasc Med Cardiovascular Medicine Brain diseases are a major burden on human health worldwide, and little is known about how most brain diseases develop. It is believed that cardiovascular diseases can affect the function of the brain, and many brain diseases are associated with heart dysfunction, which is called the heart-brain axis. Congenital heart abnormalities with anomalous hemodynamics are common treatable cardiovascular diseases. With the development of cardiovascular surgeries and interventions, the long-term survival of patients with congenital heart abnormalities continues to improve. However, physicians have reported that patients with congenital heart abnormalities have an increased risk of brain diseases in adulthood. To understand the complex association between congenital heart abnormalities and brain diseases, the paper reviews relevant clinical literature. Studies have shown that congenital heart abnormalities are associated with most brain diseases, including stroke, migraine, dementia, infection of the central nervous system, epilepsy, white matter lesions, and affective disorders. However, whether surgeries or other interventions could benefit patients with congenital heart abnormalities and brain diseases remains unclear because of limited evidence. Frontiers Media S.A. 2023-03-29 /pmc/articles/PMC10090520/ /pubmed/37063948 http://dx.doi.org/10.3389/fcvm.2023.1071820 Text en © 2023 Sha, Li, Zhang, Tang, Li, Chen and Chen. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Cardiovascular Medicine Sha, Leihao Li, Yajiao Zhang, Yunwu Tang, Yusha Li, Baichuan Chen, Yucheng Chen, Lei Heart-brain axis: Association of congenital heart abnormality and brain diseases |
title | Heart-brain axis: Association of congenital heart abnormality and brain diseases |
title_full | Heart-brain axis: Association of congenital heart abnormality and brain diseases |
title_fullStr | Heart-brain axis: Association of congenital heart abnormality and brain diseases |
title_full_unstemmed | Heart-brain axis: Association of congenital heart abnormality and brain diseases |
title_short | Heart-brain axis: Association of congenital heart abnormality and brain diseases |
title_sort | heart-brain axis: association of congenital heart abnormality and brain diseases |
topic | Cardiovascular Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090520/ https://www.ncbi.nlm.nih.gov/pubmed/37063948 http://dx.doi.org/10.3389/fcvm.2023.1071820 |
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