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Solid-phase synthesis and properties of stereocontrolled boranophosphate/phosphate and phosphorothioate/phosphate chimeric oligouridylates

This study describes the stereoselective synthesis of boranophosphate/phosphate (PB/PO) and phosphorothioate/phosphate (PS/PO) chimeric oligouridylates using the solid-phase method. Oxazaphospholidine monomer was used to construct the stereodefined PB and PS linkages. The study introduces modificati...

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Detalles Bibliográficos
Autores principales: Sato, Kazuki, Nukaga, Yohei, Wada, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090885/
https://www.ncbi.nlm.nih.gov/pubmed/37063986
http://dx.doi.org/10.1098/rsos.230095