Safety and efficacy of intracoronary artery administration of human bone marrow-derived mesenchymal stem cells in STEMI of Lee-Sung pigs—A preclinical study for supporting the feasibility of the OmniMSC-AMI phase I clinical trial

BACKGROUND: This study tested whether early left intracoronary arterial (LAD) administration of human bone marrow-derived mesenchymal stem cells (hBMMSCs, called OmniMSCs) in acute ST-segment elevation myocardial infarction (STEMI) of Lee-Sung pigs induced by 90 min balloon-occluded LAD was safe and...

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Detalles Bibliográficos
Autores principales: Chen, Wannhsin, Hou, Chun-Hsiang, Chen, Yi-Ling, Shen, Hsin-Hsin, Lin, Chen-Hsuan, Wu, Cheng-Yi, Lin, Meng-Hsueh, Liao, Chih-Ching, Huang, Jun-Jae, Yang, Chi-Yu, Li, Yi-Chen, Yip, Hon-Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091140/
https://www.ncbi.nlm.nih.gov/pubmed/37063964
http://dx.doi.org/10.3389/fcvm.2023.1153428

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