Cargando…

Stochastic disease spreading and containment policies under state-dependent probabilities

We analyze the role of disease containment policy in the form of treatment in a stochastic economic-epidemiological framework in which the probability of the occurrence of random shocks is state-dependent, namely it is related to the level of disease prevalence. Random shocks are associated with the...

Descripción completa

Detalles Bibliográficos
Autores principales: La Torre, Davide, Marsiglio, Simone, Mendivil, Franklin, Privileggi, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091343/
https://www.ncbi.nlm.nih.gov/pubmed/37360772
http://dx.doi.org/10.1007/s00199-023-01496-y
_version_ 1785023115961565184
author La Torre, Davide
Marsiglio, Simone
Mendivil, Franklin
Privileggi, Fabio
author_facet La Torre, Davide
Marsiglio, Simone
Mendivil, Franklin
Privileggi, Fabio
author_sort La Torre, Davide
collection PubMed
description We analyze the role of disease containment policy in the form of treatment in a stochastic economic-epidemiological framework in which the probability of the occurrence of random shocks is state-dependent, namely it is related to the level of disease prevalence. Random shocks are associated with the diffusion of a new strain of the disease which affects both the number of infectives and the growth rate of infection, and the probability of such shocks realization may be either increasing or decreasing in the number of infectives. We determine the optimal policy and the steady state of such a stochastic framework, which is characterized by an invariant measure supported on strictly positive prevalence levels, suggesting that complete eradication is never a possible long run outcome where instead endemicity will prevail. Our results show that: (i) independently of the features of the state-dependent probabilities, treatment allows to shift leftward the support of the invariant measure; and (ii) the features of the state-dependent probabilities affect the shape and spread of the distribution of disease prevalence over its support, allowing for a steady state outcome characterized by a distribution alternatively highly concentrated over low prevalence levels or more spread out over a larger range of prevalence (possibly higher) levels.
format Online
Article
Text
id pubmed-10091343
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Springer Berlin Heidelberg
record_format MEDLINE/PubMed
spelling pubmed-100913432023-04-14 Stochastic disease spreading and containment policies under state-dependent probabilities La Torre, Davide Marsiglio, Simone Mendivil, Franklin Privileggi, Fabio Econ Theory Research Article We analyze the role of disease containment policy in the form of treatment in a stochastic economic-epidemiological framework in which the probability of the occurrence of random shocks is state-dependent, namely it is related to the level of disease prevalence. Random shocks are associated with the diffusion of a new strain of the disease which affects both the number of infectives and the growth rate of infection, and the probability of such shocks realization may be either increasing or decreasing in the number of infectives. We determine the optimal policy and the steady state of such a stochastic framework, which is characterized by an invariant measure supported on strictly positive prevalence levels, suggesting that complete eradication is never a possible long run outcome where instead endemicity will prevail. Our results show that: (i) independently of the features of the state-dependent probabilities, treatment allows to shift leftward the support of the invariant measure; and (ii) the features of the state-dependent probabilities affect the shape and spread of the distribution of disease prevalence over its support, allowing for a steady state outcome characterized by a distribution alternatively highly concentrated over low prevalence levels or more spread out over a larger range of prevalence (possibly higher) levels. Springer Berlin Heidelberg 2023-04-12 /pmc/articles/PMC10091343/ /pubmed/37360772 http://dx.doi.org/10.1007/s00199-023-01496-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research Article
La Torre, Davide
Marsiglio, Simone
Mendivil, Franklin
Privileggi, Fabio
Stochastic disease spreading and containment policies under state-dependent probabilities
title Stochastic disease spreading and containment policies under state-dependent probabilities
title_full Stochastic disease spreading and containment policies under state-dependent probabilities
title_fullStr Stochastic disease spreading and containment policies under state-dependent probabilities
title_full_unstemmed Stochastic disease spreading and containment policies under state-dependent probabilities
title_short Stochastic disease spreading and containment policies under state-dependent probabilities
title_sort stochastic disease spreading and containment policies under state-dependent probabilities
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091343/
https://www.ncbi.nlm.nih.gov/pubmed/37360772
http://dx.doi.org/10.1007/s00199-023-01496-y
work_keys_str_mv AT latorredavide stochasticdiseasespreadingandcontainmentpoliciesunderstatedependentprobabilities
AT marsigliosimone stochasticdiseasespreadingandcontainmentpoliciesunderstatedependentprobabilities
AT mendivilfranklin stochasticdiseasespreadingandcontainmentpoliciesunderstatedependentprobabilities
AT privileggifabio stochasticdiseasespreadingandcontainmentpoliciesunderstatedependentprobabilities