Cargando…
Leveraging Multi-Ancestry Polygenic Risk Scores for Body Mass Index to Predict Antiretroviral Therapy-Induced Weight Gain*
Widespread availability of antiretroviral therapies (ART) for HIV-1 have generated considerable interest in understanding the pharmacogenomics of ART. In some individuals, ART has been associated with excessive weight gain, which disproportionately affects women of African ancestry. The underlying b...
Autores principales: | Keat, Karl, Hui, Daniel, Xiao, Brenda, Bradford, Yuki, Cindi, Zinhle, Daar, Eric S., Gulick, Roy, Riddler, Sharon A., Sinxadi, Phumla, Haas, David W., Ritchie, Marylyn D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091400/ https://www.ncbi.nlm.nih.gov/pubmed/36540980 |
Ejemplares similares
-
Tissue specificity-aware TWAS (TSA-TWAS) framework identifies novel associations with metabolic, immunologic, and virologic traits in HIV-positive adults
por: Li, Binglan, et al.
Publicado: (2021) -
Weight gain on dolutegravir: Association is not the same as causation
por: Maartens, Gary, et al.
Publicado: (2023) -
Pharmacogenetics of tenofovir renal toxicity in HIV-positive Southern Africans
por: Mateza, Somila, et al.
Publicado: (2023) -
Multiphenotype association study of patients randomized to initiate antiretroviral regimens in AIDS Clinical Trials Group protocol A5202
por: Verma, Anurag, et al.
Publicado: (2017) -
MUSSEL: Enhanced Bayesian Polygenic Risk Prediction Leveraging Information across Multiple Ancestry Groups
por: Jin, Jin, et al.
Publicado: (2023)