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The H2TH-like motif of the Escherichia coli multifunctional protein KsgA is required for DNA binding involved in DNA repair and the suppression of mutation frequencies

BACKGROUND: DNA oxidatively damaged by reactive oxygen species is repaired by base excision repair (BER) pathway proteins, with DNA glycosylases removing damaged or mismatched bases in the first step of BER. KsgA is a multifunctional protein that exhibits the activities of two enzymes, DNA glycosyla...

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Detalles Bibliográficos
Autores principales: Hayashi, Yuichiro, Funakoshi, Masafumi, Hirosawa, Kaname, Zhang-Akiyama, Qiu-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091538/
https://www.ncbi.nlm.nih.gov/pubmed/37041652
http://dx.doi.org/10.1186/s41021-023-00266-5