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The H2TH-like motif of the Escherichia coli multifunctional protein KsgA is required for DNA binding involved in DNA repair and the suppression of mutation frequencies
BACKGROUND: DNA oxidatively damaged by reactive oxygen species is repaired by base excision repair (BER) pathway proteins, with DNA glycosylases removing damaged or mismatched bases in the first step of BER. KsgA is a multifunctional protein that exhibits the activities of two enzymes, DNA glycosyla...
Autores principales: | Hayashi, Yuichiro, Funakoshi, Masafumi, Hirosawa, Kaname, Zhang-Akiyama, Qiu-Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091538/ https://www.ncbi.nlm.nih.gov/pubmed/37041652 http://dx.doi.org/10.1186/s41021-023-00266-5 |
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