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HIGD2A silencing impairs hepatocellular carcinoma growth via inhibiting mitochondrial function and the MAPK/ERK pathway

BACKGROUND: The Hypoxia inducible gene domain family member 2A (HIGD2A) protein is indispensable for the assembly of the mitochondrial respiratory supercomplex, which has been implicated in cell proliferation and cell survival under hypoxic conditions. Because the liver has a naturally low oxygen mi...

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Detalles Bibliográficos
Autores principales:	Huang, Kuiyuan, Liu, Ziying, Xie, Zhanglian, Li, Xiaoran, Zhang, Haixing, Chen, Yu, Wang, Yiran, Lin, Zimo, Li, Chuanjiang, Liu, Hongyan, Zhang, Xiaoyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091548/ https://www.ncbi.nlm.nih.gov/pubmed/37041638 http://dx.doi.org/10.1186/s12967-023-04105-7

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