Extracellular vesicles secreted from bone metastatic renal cell carcinoma promote angiogenesis and endothelial gap formation in bone marrow in a time-dependent manner in a preclinical mouse model

INTRODUCTION: Bone is a major metastatic site of renal cell carcinoma (RCC). Recently, it is well recognized that bone metastatic tumor cells remodel bone marrow vasculature. However, the precise mechanism underlying cell-cell communication between bone metastatic RCC and the cells in bone marrow re...

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Detalles Bibliográficos
Autores principales: Takeda, Masashi, Sakamoto, Hiromasa, Shibasaki, Noboru, Fukui, Tomohiro, Magaribuchi, Toshihiro, Sumiyoshi, Takayuki, Utsunomiya, Noriaki, Sawada, Atsuro, Goto, Takayuki, Kobayashi, Takashi, Ueda, Koji, Yamasaki, Toshinari, Ogawa, Osamu, Akamatsu, Shusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091619/
https://www.ncbi.nlm.nih.gov/pubmed/37064121
http://dx.doi.org/10.3389/fonc.2023.1139049

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