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Alpha-lipoic acid supplementation corrects pathological alterations in cellular models of pantothenate kinase-associated neurodegeneration with residual PANK2 expression levels

BACKGROUND: Neurodegeneration with brain iron accumulation (NBIA) disorders are a group of neurodegenerative diseases that have in common the accumulation of iron in the basal nuclei of the brain which are essential components of the extrapyramidal system. Frequent symptoms are progressive spasticit...

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Detalles Bibliográficos
Autores principales: Talaverón-Rey, Marta, Álvarez-Córdoba, Mónica, Villalón-García, Irene, Povea-Cabello, Suleva, Suárez-Rivero, Juan M., Gómez-Fernández, David, Romero-González, Ana, Suárez-Carrillo, Alejandra, Munuera-Cabeza, Manuel, Cilleros-Holgado, Paula, Reche-López, Diana, Piñero-Pérez, Rocío, Sánchez-Alcázar, José A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091671/
https://www.ncbi.nlm.nih.gov/pubmed/37046296
http://dx.doi.org/10.1186/s13023-023-02687-5