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Risk-based allocation of COVID-19 personal protective equipment under supply shortages

The COVID-19 outbreak put healthcare systems across the globe under immense pressure to meet the unprecedented demand for critical supplies and personal protective equipment (PPE). The traditional cost-effective supply chain paradigm failed to respond to the increased demand, putting healthcare work...

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Autores principales: Baloch, Gohram, Gzara, Fatma, Elhedhli, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091728/
https://www.ncbi.nlm.nih.gov/pubmed/37284205
http://dx.doi.org/10.1016/j.ejor.2023.04.001
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author Baloch, Gohram
Gzara, Fatma
Elhedhli, Samir
author_facet Baloch, Gohram
Gzara, Fatma
Elhedhli, Samir
author_sort Baloch, Gohram
collection PubMed
description The COVID-19 outbreak put healthcare systems across the globe under immense pressure to meet the unprecedented demand for critical supplies and personal protective equipment (PPE). The traditional cost-effective supply chain paradigm failed to respond to the increased demand, putting healthcare workers (HCW) at a much higher infection risk relative to the general population. Recognizing PPE shortages and high infection risk for HCWs, the World Health Organization (WHO) recommends allocations based on ethical principles. In this paper, we model the infection risk for HCWs as a function of usage and use it as the basis for distribution planning that balances government procurement decisions, hospitals’ PPE usage policies, and WHO ethical allocation guidelines. We propose an infection risk model that integrates PPE allocation decisions with disease progression estimates to quantify infection risk among HCWs. The proposed risk function is used to derive closed-form allocation decisions under WHO ethical guidelines in both deterministic and stochastic settings. The modelling is then extended to dynamic distribution planning. Although nonlinear, we reformulate the resulting model to make it solvable using off-the-shelf software. The risk function successfully accounts for virus prevalence in space and in time and leads to allocations that are sensitive to the differences between regions. Comparative analysis shows that the allocation policies lead to significantly different levels of infection risk, especially under high virus prevalence. The best-outcome allocation policy that aims to minimize the total infected cases outperforms other policies under this objective and that of minimizing the maximum number of infections per period.
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spelling pubmed-100917282023-04-13 Risk-based allocation of COVID-19 personal protective equipment under supply shortages Baloch, Gohram Gzara, Fatma Elhedhli, Samir Eur J Oper Res Production, Manufacturing, Transportation and Logistics The COVID-19 outbreak put healthcare systems across the globe under immense pressure to meet the unprecedented demand for critical supplies and personal protective equipment (PPE). The traditional cost-effective supply chain paradigm failed to respond to the increased demand, putting healthcare workers (HCW) at a much higher infection risk relative to the general population. Recognizing PPE shortages and high infection risk for HCWs, the World Health Organization (WHO) recommends allocations based on ethical principles. In this paper, we model the infection risk for HCWs as a function of usage and use it as the basis for distribution planning that balances government procurement decisions, hospitals’ PPE usage policies, and WHO ethical allocation guidelines. We propose an infection risk model that integrates PPE allocation decisions with disease progression estimates to quantify infection risk among HCWs. The proposed risk function is used to derive closed-form allocation decisions under WHO ethical guidelines in both deterministic and stochastic settings. The modelling is then extended to dynamic distribution planning. Although nonlinear, we reformulate the resulting model to make it solvable using off-the-shelf software. The risk function successfully accounts for virus prevalence in space and in time and leads to allocations that are sensitive to the differences between regions. Comparative analysis shows that the allocation policies lead to significantly different levels of infection risk, especially under high virus prevalence. The best-outcome allocation policy that aims to minimize the total infected cases outperforms other policies under this objective and that of minimizing the maximum number of infections per period. Elsevier B.V. 2023-11-01 2023-04-12 /pmc/articles/PMC10091728/ /pubmed/37284205 http://dx.doi.org/10.1016/j.ejor.2023.04.001 Text en © 2023 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Production, Manufacturing, Transportation and Logistics
Baloch, Gohram
Gzara, Fatma
Elhedhli, Samir
Risk-based allocation of COVID-19 personal protective equipment under supply shortages
title Risk-based allocation of COVID-19 personal protective equipment under supply shortages
title_full Risk-based allocation of COVID-19 personal protective equipment under supply shortages
title_fullStr Risk-based allocation of COVID-19 personal protective equipment under supply shortages
title_full_unstemmed Risk-based allocation of COVID-19 personal protective equipment under supply shortages
title_short Risk-based allocation of COVID-19 personal protective equipment under supply shortages
title_sort risk-based allocation of covid-19 personal protective equipment under supply shortages
topic Production, Manufacturing, Transportation and Logistics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091728/
https://www.ncbi.nlm.nih.gov/pubmed/37284205
http://dx.doi.org/10.1016/j.ejor.2023.04.001
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