Calcium‐channel blockers: Clinical outcome associations with reported pharmacogenetics variants in 32 000 patients

AIMS: Pharmacogenetic variants impact dihydropyridine calcium‐channel blockers (dCCBs; e.g., amlodipine) treatment efficacy, yet evidence on clinical outcomes in routine primary care is limited. Reported associations in pharmacogenomics knowledge base PharmGKB have weak supporting evidence. We aimed...

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Detalles Bibliográficos
Autores principales: Türkmen, Deniz, Masoli, Jane A. H., Delgado, João, Kuo, Chia‐Ling, Bowden, Jack, Melzer, David, Pilling, Luke C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091789/
https://www.ncbi.nlm.nih.gov/pubmed/36134646
http://dx.doi.org/10.1111/bcp.15541

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