Improving the response to oxaliplatin by targeting chemotherapy-induced CLDN1 in resistant metastatic colorectal cancer cells

BACKGROUND: Tumor resistance is a frequent cause of therapy failure and remains a major challenge for the long-term management of colorectal cancer (CRC). The aim of this study was to determine the implication of the tight junctional protein claudin 1 (CLDN1) in the acquired resistance to chemothera...

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Detalles Bibliográficos
Autores principales: Cherradi, Sara, Garambois, Véronique, Marines, Johanna, Andrade, Augusto Faria, Fauvre, Alexandra, Morand, Olivia, Fargal, Manon, Mancouri, Ferial, Ayrolles-Torro, Adeline, Vezzo-Vié, Nadia, Jarlier, Marta, Loussaint, Gerald, Huvelle, Steve, Joubert, Nicolas, Mazard, Thibault, Gongora, Céline, Pourquier, Philippe, Boissière-Michot, Florence, Rio, Maguy Del
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091849/
https://www.ncbi.nlm.nih.gov/pubmed/37041570
http://dx.doi.org/10.1186/s13578-023-01015-5

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