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MEK inhibitors as novel host-targeted antivirals with a dual-benefit mode of action against hyperinflammatory respiratory viral diseases

Acute hyperinflammatory virus infections, such as influenza or coronavirus disease-19, are still a major health burden worldwide. In these diseases, a massive overproduction of pro-inflammatory cytokines and chemokines (cytokine storm syndrome) determine the severity of the disease, especially in la...

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Detalles Bibliográficos
Autores principales: Ludwig, Stephan, Pleschka, Stephan, Planz, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091867/
https://www.ncbi.nlm.nih.gov/pubmed/36841033
http://dx.doi.org/10.1016/j.coviro.2023.101304