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Transformable prodrug nanoplatform via tumor microenvironment modulation and immune checkpoint blockade potentiates immunogenic cell death mediated cancer immunotherapy
Rationale: Chemoimmunotherapy is a promising approach in cancer immunotherapy. However, its therapeutic efficacy is restricted by high reactive oxygen species (ROS) levels, an abundance of cancer-associated fibroblasts (CAFs) in tumor microenvironment (TME) as well as immune checkpoints for escaping...
Autores principales: | Yang, Weijing, Yi, Jinmeng, Zhu, Rongrong, Guo, Yichen, Zhang, Kaixin, Cao, Yongjian, Li, Xinyan, Zhang, Jinjie, Zhang, Zhenzhong, Li, Yongjuan, Chen, Xiaoyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091884/ https://www.ncbi.nlm.nih.gov/pubmed/37064869 http://dx.doi.org/10.7150/thno.83912 |
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