Cargando…
Combination of PD‐1/PD‐L1 checkpoint inhibition and dendritic cell therapy in mice models and in patients with mesothelioma
Immunotherapy with anti‐PD1/PD‐L1 is effective in only a subgroup of patients with malignant pleural mesothelioma (MPM). We investigated the efficacy of a combination of anti‐PD1/PD‐L1 and dendritic cell (DC) therapy to optimally induce effective anti‐tumor immunity in MPM in both humans and mice. D...
Autores principales: | van Gulijk, Mandy, Belderbos, Bob, Dumoulin, Daphne, Cornelissen, Robin, Bezemer, Koen, Klaase, Larissa, Dammeijer, Floris, Aerts, Joachim |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092125/ https://www.ncbi.nlm.nih.gov/pubmed/36104949 http://dx.doi.org/10.1002/ijc.34293 |
Ejemplares similares
-
Combination Strategies to Optimize Efficacy of Dendritic Cell-Based Immunotherapy
por: van Gulijk, Mandy, et al.
Publicado: (2018) -
Long-Term Follow-Up of Mesothelioma Patients Treated with Dendritic Cell Therapy in Three Phase I/II Trials
por: Dumoulin, Daphne W., et al.
Publicado: (2021) -
Discontinuation of anti‐PD‐1 monotherapy in advanced melanoma—Outcomes of daily clinical practice
por: van Zeijl, Michiel C. T., et al.
Publicado: (2021) -
Relationship between protein biomarkers of chemotherapy response and microsatellite status, tumor mutational burden and PD‐L1 expression in cancer patients
por: Nikanjam, Mina, et al.
Publicado: (2019) -
Immune monitoring in mesothelioma patients identifies novel immune-modulatory functions of gemcitabine associating with clinical response
por: Dammeijer, Floris, et al.
Publicado: (2021)