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The panorama of cerebral palsy in Sweden part XIII shows declining prevalence in birth‐years 2011–2014

AIM: To describe epidemiology and characteristics of cerebral palsy (CP) in western Sweden 1954–2014. METHODS: Population‐based study covering 105 935 live births in the area in 2011–2014. Birth characteristics, neuroimaging findings and outcome were analysed and prevalence calculated. Non‐parametri...

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Autores principales: Himmelmann, Kate, Påhlman, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092185/
https://www.ncbi.nlm.nih.gov/pubmed/36153696
http://dx.doi.org/10.1111/apa.16548
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author Himmelmann, Kate
Påhlman, Magnus
author_facet Himmelmann, Kate
Påhlman, Magnus
author_sort Himmelmann, Kate
collection PubMed
description AIM: To describe epidemiology and characteristics of cerebral palsy (CP) in western Sweden 1954–2014. METHODS: Population‐based study covering 105 935 live births in the area in 2011–2014. Birth characteristics, neuroimaging findings and outcome were analysed and prevalence calculated. Non‐parametric methods were used for group comparisons. RESULTS: CP was diagnosed in 192 children. Crude prevalence had decreased to 1.81 per 1000 live births (p = 0.0067). Gestational age‐specific prevalence for <28 gestational weeks was 74.8 per 1000 live births, 46.6 for 28–31 weeks, 5.8 for 32–36 weeks and 1.1 per 1000 for >36 weeks of gestation. Hemiplegia, found in 36.2%, had declined (p = 0.03). Diplegia was found in 36.2% and tetraplegia 5.3%. Dyskinetic CP accounted for 18.6% and ataxia for 3.7%. Neuroimaging revealed maldevelopments in 14%, white matter lesions in 44%, cortical/subcortical lesions in 13% and basal ganglia lesions in 17%. Prenatal aetiology was considered in 34%, peri‐ or neonatal in 48%, while in 18% aetiological period remained unclassified. Motor outcome in children who needed neonatal care had improved (p = 0.04). Motor function in dyskinetic CP had improved compared to previous cohorts (p = 0.008). CONCLUSION: The prevalence of CP has declined, mainly in term‐born and in hemiplegia, and motor severity has changed compared to previous cohorts.
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spelling pubmed-100921852023-04-13 The panorama of cerebral palsy in Sweden part XIII shows declining prevalence in birth‐years 2011–2014 Himmelmann, Kate Påhlman, Magnus Acta Paediatr ORIGINAL ARTICLES & BRIEF REPORTS AIM: To describe epidemiology and characteristics of cerebral palsy (CP) in western Sweden 1954–2014. METHODS: Population‐based study covering 105 935 live births in the area in 2011–2014. Birth characteristics, neuroimaging findings and outcome were analysed and prevalence calculated. Non‐parametric methods were used for group comparisons. RESULTS: CP was diagnosed in 192 children. Crude prevalence had decreased to 1.81 per 1000 live births (p = 0.0067). Gestational age‐specific prevalence for <28 gestational weeks was 74.8 per 1000 live births, 46.6 for 28–31 weeks, 5.8 for 32–36 weeks and 1.1 per 1000 for >36 weeks of gestation. Hemiplegia, found in 36.2%, had declined (p = 0.03). Diplegia was found in 36.2% and tetraplegia 5.3%. Dyskinetic CP accounted for 18.6% and ataxia for 3.7%. Neuroimaging revealed maldevelopments in 14%, white matter lesions in 44%, cortical/subcortical lesions in 13% and basal ganglia lesions in 17%. Prenatal aetiology was considered in 34%, peri‐ or neonatal in 48%, while in 18% aetiological period remained unclassified. Motor outcome in children who needed neonatal care had improved (p = 0.04). Motor function in dyskinetic CP had improved compared to previous cohorts (p = 0.008). CONCLUSION: The prevalence of CP has declined, mainly in term‐born and in hemiplegia, and motor severity has changed compared to previous cohorts. John Wiley and Sons Inc. 2022-10-03 2023-01 /pmc/articles/PMC10092185/ /pubmed/36153696 http://dx.doi.org/10.1111/apa.16548 Text en © 2022 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle ORIGINAL ARTICLES & BRIEF REPORTS
Himmelmann, Kate
Påhlman, Magnus
The panorama of cerebral palsy in Sweden part XIII shows declining prevalence in birth‐years 2011–2014
title The panorama of cerebral palsy in Sweden part XIII shows declining prevalence in birth‐years 2011–2014
title_full The panorama of cerebral palsy in Sweden part XIII shows declining prevalence in birth‐years 2011–2014
title_fullStr The panorama of cerebral palsy in Sweden part XIII shows declining prevalence in birth‐years 2011–2014
title_full_unstemmed The panorama of cerebral palsy in Sweden part XIII shows declining prevalence in birth‐years 2011–2014
title_short The panorama of cerebral palsy in Sweden part XIII shows declining prevalence in birth‐years 2011–2014
title_sort panorama of cerebral palsy in sweden part xiii shows declining prevalence in birth‐years 2011–2014
topic ORIGINAL ARTICLES & BRIEF REPORTS
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092185/
https://www.ncbi.nlm.nih.gov/pubmed/36153696
http://dx.doi.org/10.1111/apa.16548
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