Cargando…

Uncovering mechanisms of brain inflammation in Alzheimer's disease with APOE4: Application of single cell‐type lipidomics

A chronic state of unresolved inflammation in Alzheimer's disease (AD) is intrinsically involved with the remodeling of brain lipids. This review highlights the effect of carrying the apolipoprotein E ε4 allele (APOE4) on various brain cell types in promoting an unresolved inflammatory state. A...

Descripción completa

Detalles Bibliográficos
Autores principales: Asante, Isaac, Louie, Stan, Yassine, Hussein N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092192/
https://www.ncbi.nlm.nih.gov/pubmed/36200578
http://dx.doi.org/10.1111/nyas.14907