Effect of RNS60 in amyotrophic lateral sclerosis: a phase II multicentre, randomized, double‐blind, placebo‐controlled trial

BACKGROUND AND PURPOSE: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with limited treatment options. RNS60 is an immunomodulatory and neuroprotective investigational product that has shown efficacy in animal models of ALS and other neurodegenerative diseases. Its administ...

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Detalles Bibliográficos
Autores principales: Beghi, Ettore, Pupillo, Elisabetta, Bianchi, Elisa, Bonetto, Valentina, Luotti, Silvia, Pasetto, Laura, Bendotti, Caterina, Tortarolo, Massimo, Sironi, Francesca, Camporeale, Laura, Sherman, Alexander V., Paganoni, Sabrina, Scognamiglio, Ada, De Marchi, Fabiola, Bongioanni, Paolo, Del Carratore, Renata, Caponnetto, Claudia, Diamanti, Luca, Martinelli, Daniele, Calvo, Andrea, Filosto, Massimiliano, Padovani, Alessandro, Piccinelli, Stefano Cotti, Ricci, Claudia, Dalla Giacoma, Stefania, De Angelis, Nicoletta, Inghilleri, Maurizio, Spataro, Rossella, La Bella, Vincenzo, Logroscino, Giancarlo, Lunetta, Christian, Tarlarini, Claudia, Mandrioli, Jessica, Martinelli, Ilaria, Simonini, Cecilia, Zucchi, Elisabetta, Monsurrò, Maria Rosaria, Ricciardi, Dario, Trojsi, Francesca, Riva, Nilo, Filippi, Massimo, Simone, Isabella Laura, Sorarù, Gianni, Spera, Cristina, Florio, Lucia, Messina, Sonia, Russo, Massimo, Siciliano, Gabriele, Conte, Amelia, Saddi, Maria Valeria, Carboni, Nicola, Mazzini, Letizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
ALS and frontotemporal dementia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092300/
https://www.ncbi.nlm.nih.gov/pubmed/36148821
http://dx.doi.org/10.1111/ene.15573

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