Axonal response of mitochondria to demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis

AIMS: Axonal injury in multiple sclerosis (MS) and experimental models is most frequently detected in acutely demyelinating lesions. We recently reported a compensatory neuronal response, where mitochondria move to the acutely demyelinated axon and increase the mitochondrial content following lysole...

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Detalles Bibliográficos
Autores principales: Licht‐Mayer, Simon, Campbell, Graham R., Mehta, Arpan R., McGill, Katie, Symonds, Alex, Al‐Azki, Sarah, Pryce, Gareth, Zandee, Stephanie, Zhao, Chao, Kipp, Markus, Smith, Kenneth J., Baker, David, Altmann, Daniel, Anderton, Stephen M., Kap, Yolanda S., Laman, Jon D., 't Hart, Bert A., Rodriguez, Moses, Franklin, Robin J. M., Chandran, Siddharthan, Lassmann, Hans, Trapp, Bruce D., Mahad, Don J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092519/
https://www.ncbi.nlm.nih.gov/pubmed/36181265
http://dx.doi.org/10.1111/nan.12851

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