Alkyne Activation in the Diversity Oriented Synthesis of sp(2)‐Rich Scaffolds: A Biased Library Approach for Targeting Polynucleotides (DNA/RNA)

Polynucleotides, DNA and RNA (mRNA and non‐coding RNAs) are critically involved in the molecular pathways of disease. Small molecule binding interactions with polynucleotides can modify functional polynucleotide topologies and/or their interactions with proteins. Current approaches to library design...

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Detalles Bibliográficos
Autores principales: Chen, Shuqi, Priebbenow, Daniel L., Somkhit, Julie, Scullino, Carmen V., Agama, Keli, Pommier, Yves, Flynn, Bernard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092545/
https://www.ncbi.nlm.nih.gov/pubmed/36069042
http://dx.doi.org/10.1002/chem.202201925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092545/
https://www.ncbi.nlm.nih.gov/pubmed/36069042
http://dx.doi.org/10.1002/chem.202201925

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