Cargando…
Alkyne Activation in the Diversity Oriented Synthesis of sp(2)‐Rich Scaffolds: A Biased Library Approach for Targeting Polynucleotides (DNA/RNA)
Polynucleotides, DNA and RNA (mRNA and non‐coding RNAs) are critically involved in the molecular pathways of disease. Small molecule binding interactions with polynucleotides can modify functional polynucleotide topologies and/or their interactions with proteins. Current approaches to library design...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092545/ https://www.ncbi.nlm.nih.gov/pubmed/36069042 http://dx.doi.org/10.1002/chem.202201925 |