A Simple Colorimetric Assay of Bleomycin‐Mediated DNA Cleavage Utilizing Double‐Stranded DNA‐Modified Gold Nanoparticles

A colorimetric assay of DNA cleavage by bleomycin (BLM) derivatives was developed utilizing high colloidal stability on double‐stranded (ds) DNA‐modified gold nanoparticles (dsDNA‐AuNPs) possessing a cleavage site. The assay was performed using dsDNA‐AuNPs treated with inactive BLM or activated BLM...

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Detalles Bibliográficos
Autores principales: Akiyama, Yoshitsugu, Kimura, Kazunori, Komatsu, Syuuhei, Takarada, Tohru, Maeda, Mizuo, Kikuchi, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092608/
https://www.ncbi.nlm.nih.gov/pubmed/36156837
http://dx.doi.org/10.1002/cbic.202200451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092608/
https://www.ncbi.nlm.nih.gov/pubmed/36156837
http://dx.doi.org/10.1002/cbic.202200451

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