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Importin α/β promote Kif18B microtubule association and enhance microtubule destabilization activity

Tight regulation of microtubule (MT) dynamics is necessary for proper spindle assembly and chromosome segregation. The MT destabilizing Kinesin-8, Kif18B, controls astral MT dynamics and spindle positioning. Kif18B interacts with importin α/β as well as with the plus-tip tracking protein EB1, but ho...

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Detalles Bibliográficos
Autores principales:	Shrestha, Sanjay, Ems-McClung, Stephanie C., Hazelbaker, Mark A., Yount, Amber L., Shaw, Sidney L., Walczak, Claire E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092650/ https://www.ncbi.nlm.nih.gov/pubmed/36790918 http://dx.doi.org/10.1091/mbc.E22-03-0113

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