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Recent advances and challenges in temperature monitoring and control in microfluidic devices
Temperature is a critical—yet sometimes overlooked—parameter in microfluidics. Microfluidic devices can experience heating inside their channels during operation due to underlying physicochemical phenomena occurring therein. Such heating, whether required or not, must be monitored to ensure adequate...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092670/ https://www.ncbi.nlm.nih.gov/pubmed/36205631 http://dx.doi.org/10.1002/elps.202200162 |
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author | Dos‐Reis‐Delgado, Alejandro A. Carmona‐Dominguez, Andrea Sosa‐Avalos, Gerardo Jimenez‐Saaib, Ivan H. Villegas‐Cantu, Karen E. Gallo‐Villanueva, Roberto C. Perez‐Gonzalez, Víctor H. |
author_facet | Dos‐Reis‐Delgado, Alejandro A. Carmona‐Dominguez, Andrea Sosa‐Avalos, Gerardo Jimenez‐Saaib, Ivan H. Villegas‐Cantu, Karen E. Gallo‐Villanueva, Roberto C. Perez‐Gonzalez, Víctor H. |
author_sort | Dos‐Reis‐Delgado, Alejandro A. |
collection | PubMed |
description | Temperature is a critical—yet sometimes overlooked—parameter in microfluidics. Microfluidic devices can experience heating inside their channels during operation due to underlying physicochemical phenomena occurring therein. Such heating, whether required or not, must be monitored to ensure adequate device operation. Therefore, different techniques have been developed to measure and control temperature in microfluidic devices. In this contribution, the operating principles and applications of these techniques are reviewed. Temperature‐monitoring instruments revised herein include thermocouples, thermistors, and custom‐built temperature sensors. Of these, thermocouples exhibit the widest operating range; thermistors feature the highest accuracy; and custom‐built temperature sensors demonstrate the best transduction. On the other hand, temperature control methods can be classified as external‐ or integrated‐methods. Within the external methods, microheaters are shown to be the most adequate when working with biological samples, whereas Peltier elements are most useful in applications that require the development of temperature gradients. In contrast, integrated methods are based on chemical and physical properties, structural arrangements, which are characterized by their low fabrication cost and a wide range of applications. The potential integration of these platforms with the Internet of Things technology is discussed as a potential new trend in the field. |
format | Online Article Text |
id | pubmed-10092670 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100926702023-04-13 Recent advances and challenges in temperature monitoring and control in microfluidic devices Dos‐Reis‐Delgado, Alejandro A. Carmona‐Dominguez, Andrea Sosa‐Avalos, Gerardo Jimenez‐Saaib, Ivan H. Villegas‐Cantu, Karen E. Gallo‐Villanueva, Roberto C. Perez‐Gonzalez, Víctor H. Electrophoresis Miniaturization Temperature is a critical—yet sometimes overlooked—parameter in microfluidics. Microfluidic devices can experience heating inside their channels during operation due to underlying physicochemical phenomena occurring therein. Such heating, whether required or not, must be monitored to ensure adequate device operation. Therefore, different techniques have been developed to measure and control temperature in microfluidic devices. In this contribution, the operating principles and applications of these techniques are reviewed. Temperature‐monitoring instruments revised herein include thermocouples, thermistors, and custom‐built temperature sensors. Of these, thermocouples exhibit the widest operating range; thermistors feature the highest accuracy; and custom‐built temperature sensors demonstrate the best transduction. On the other hand, temperature control methods can be classified as external‐ or integrated‐methods. Within the external methods, microheaters are shown to be the most adequate when working with biological samples, whereas Peltier elements are most useful in applications that require the development of temperature gradients. In contrast, integrated methods are based on chemical and physical properties, structural arrangements, which are characterized by their low fabrication cost and a wide range of applications. The potential integration of these platforms with the Internet of Things technology is discussed as a potential new trend in the field. John Wiley and Sons Inc. 2022-10-25 2023-01 /pmc/articles/PMC10092670/ /pubmed/36205631 http://dx.doi.org/10.1002/elps.202200162 Text en © 2022 The Authors. Electrophoresis published by Wiley‐VCH GmbH. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Miniaturization Dos‐Reis‐Delgado, Alejandro A. Carmona‐Dominguez, Andrea Sosa‐Avalos, Gerardo Jimenez‐Saaib, Ivan H. Villegas‐Cantu, Karen E. Gallo‐Villanueva, Roberto C. Perez‐Gonzalez, Víctor H. Recent advances and challenges in temperature monitoring and control in microfluidic devices |
title | Recent advances and challenges in temperature monitoring and control in microfluidic devices |
title_full | Recent advances and challenges in temperature monitoring and control in microfluidic devices |
title_fullStr | Recent advances and challenges in temperature monitoring and control in microfluidic devices |
title_full_unstemmed | Recent advances and challenges in temperature monitoring and control in microfluidic devices |
title_short | Recent advances and challenges in temperature monitoring and control in microfluidic devices |
title_sort | recent advances and challenges in temperature monitoring and control in microfluidic devices |
topic | Miniaturization |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092670/ https://www.ncbi.nlm.nih.gov/pubmed/36205631 http://dx.doi.org/10.1002/elps.202200162 |
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