BAP31 depletion inhibited adipogenesis, repressed lipolysis and promoted lipid droplets abnormal growth via attenuating Perilipin1 proteasomal degradation

BAP31 expression was robustly decreased in obese white adipose tissue (WAT). To investigate the roles of BAP31 in lipid metabolism, adipocyte-specific conditional knockout mice (BAP31-ASKO) were generated. BAP31-ASKO mice grow normally as controls, but exhibited reduced lipid accumulation in WAT. Hi...

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Detalles Bibliográficos
Autores principales: Wei, Xueying, Li, Liya, Zhao, Jie, Huo, Yan, Hu, Xiaodi, Lu, Jingyi, Pi, Jingbo, Zhang, Wei, Xu, Lisheng, Yao, Yudong, Xu, Jialin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092757/
https://www.ncbi.nlm.nih.gov/pubmed/37063427
http://dx.doi.org/10.7150/ijbs.82178

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