PI3K/ c-Myc/AFF4 axis promotes pancreatic tumorigenesis through fueling nucleotide metabolism

MLL-AFF4 fusion gene has been discovered in acute leukemia, whether AFF4 alone plays a role in tumor, especially pancreatic tumorigenesis, is still elusive. Increasing evidence suggests that cancer cells altered nucleotide metabolism during tumorigenesis. In present study, we observed AFF4 overexpre...

Descripción completa

Detalles Bibliográficos
Autores principales: Ni, Chenming, Liu, Wenyu, Zheng, Kailian, Guo, Shiwei, Song, Bin, Jing, Wei, Li, Gang, Li, Bo, Ni, Canrong, Shi, Keqing, Jin, Gang, Yu, Guanzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092763/
https://www.ncbi.nlm.nih.gov/pubmed/37063434
http://dx.doi.org/10.7150/ijbs.77150

Ejemplares similares

Ejemplares similares