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SCF/c-Kit-activated signaling and angiogenesis require Gαi1 and Gαi3

The stem cell factor (SCF) binds to c-Kit in endothelial cells, thus activating downstream signaling and angiogenesis. Herein, we examined the role of G protein subunit alpha inhibitory (Gαi) proteins in this process. In MEFs and HUVECs, Gαi1/3 was associated with SCF-activated c-Kit, promoting c-Ki...

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Detalles Bibliográficos
Autores principales:	Shan, Hua-jian, Jiang, Kun, Zhao, Ming-zhi, Deng, Wen-jing, Cao, Wen-hao, Li, Jia-jun, Li, Ke-ran, She, Chang, Luo, Wei-feng, Yao, Jin, Zhou, Xiao-zhong, Zhang, Dan, Cao, Cong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092767/ https://www.ncbi.nlm.nih.gov/pubmed/37063428 http://dx.doi.org/10.7150/ijbs.82855

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