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M1 Microglia-derived Exosomes Promote Activation of Resting Microglia and Amplifies Proangiogenic Effects through Irf1/miR-155-5p/Socs1 Axis in the Retina

Activation of microglia plays a key role in the development of neovascular retinal diseases. Therefore, it is essential to reveal its pathophysiological and molecular mechanisms to interfere with disease progression. Here a publicly available single-cell RNA sequencing dataset is used to identify th...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Wang, Xiao, Cui, Zedu, Luo, Qian, Jiang, Zihua, Huang, Yuke, Jiang, Jingyi, Qiu, Jin, Li, Yan, Yu, Keming, Zhuang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092772/
https://www.ncbi.nlm.nih.gov/pubmed/37063422
http://dx.doi.org/10.7150/ijbs.79784