NLRP3 Inflammasome Mediates Silica-induced Lung Epithelial Injury and Aberrant Regeneration in Lung Stem/Progenitor Cell-derived Organotypic Models

Silica-induced lung epithelial injury and fibrosis are vital pathogeneses of silicosis. Although the NOD-like receptor protein 3 (NLRP3) inflammasome contributes to silica-induced chronic lung inflammation, its role in epithelial injury and regeneration remains unclear. Here, using mouse lung stem/p...

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Detalles Bibliográficos
Autores principales: Zhou, Hong, Zhang, Qun, Huang, Wen, Zhou, Shulan, Wang, Yanli, Zeng, Xiaoning, Wang, Hong, Xie, Weiping, Kong, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092774/
https://www.ncbi.nlm.nih.gov/pubmed/37063430
http://dx.doi.org/10.7150/ijbs.80605

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