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Fabrication and Functionalisation of Nanocarbon‐Based Field‐Effect Transistor Biosensors

Nanocarbon‐based field‐effect transistor (NC‐FET) biosensors are at the forefront of future diagnostic technology. By integrating biological molecules with electrically conducting carbon‐based platforms, high sensitivity real‐time multiplexed sensing is possible. Combined with their small footprint,...

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Detalles Bibliográficos
Autores principales: Lee, Chang‐Seuk, Gwyther, Rebecca E. A., Freeley, Mark, Jones, Dafydd, Palma, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092808/
https://www.ncbi.nlm.nih.gov/pubmed/36193790
http://dx.doi.org/10.1002/cbic.202200282
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author Lee, Chang‐Seuk
Gwyther, Rebecca E. A.
Freeley, Mark
Jones, Dafydd
Palma, Matteo
author_facet Lee, Chang‐Seuk
Gwyther, Rebecca E. A.
Freeley, Mark
Jones, Dafydd
Palma, Matteo
author_sort Lee, Chang‐Seuk
collection PubMed
description Nanocarbon‐based field‐effect transistor (NC‐FET) biosensors are at the forefront of future diagnostic technology. By integrating biological molecules with electrically conducting carbon‐based platforms, high sensitivity real‐time multiplexed sensing is possible. Combined with their small footprint, portability, ease of use, and label‐free sensing mechanisms, NC‐FETs are prime candidates for the rapidly expanding areas of point‐of‐care testing, environmental monitoring and biosensing as a whole. In this review we provide an overview of the basic operational mechanisms behind NC‐FETs, synthesis and fabrication of FET devices, and developments in functionalisation strategies for biosensing applications.
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spelling pubmed-100928082023-04-13 Fabrication and Functionalisation of Nanocarbon‐Based Field‐Effect Transistor Biosensors Lee, Chang‐Seuk Gwyther, Rebecca E. A. Freeley, Mark Jones, Dafydd Palma, Matteo Chembiochem Reviews Nanocarbon‐based field‐effect transistor (NC‐FET) biosensors are at the forefront of future diagnostic technology. By integrating biological molecules with electrically conducting carbon‐based platforms, high sensitivity real‐time multiplexed sensing is possible. Combined with their small footprint, portability, ease of use, and label‐free sensing mechanisms, NC‐FETs are prime candidates for the rapidly expanding areas of point‐of‐care testing, environmental monitoring and biosensing as a whole. In this review we provide an overview of the basic operational mechanisms behind NC‐FETs, synthesis and fabrication of FET devices, and developments in functionalisation strategies for biosensing applications. John Wiley and Sons Inc. 2022-11-03 2022-12-05 /pmc/articles/PMC10092808/ /pubmed/36193790 http://dx.doi.org/10.1002/cbic.202200282 Text en © 2022 The Authors. ChemBioChem published by Wiley-VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Lee, Chang‐Seuk
Gwyther, Rebecca E. A.
Freeley, Mark
Jones, Dafydd
Palma, Matteo
Fabrication and Functionalisation of Nanocarbon‐Based Field‐Effect Transistor Biosensors
title Fabrication and Functionalisation of Nanocarbon‐Based Field‐Effect Transistor Biosensors
title_full Fabrication and Functionalisation of Nanocarbon‐Based Field‐Effect Transistor Biosensors
title_fullStr Fabrication and Functionalisation of Nanocarbon‐Based Field‐Effect Transistor Biosensors
title_full_unstemmed Fabrication and Functionalisation of Nanocarbon‐Based Field‐Effect Transistor Biosensors
title_short Fabrication and Functionalisation of Nanocarbon‐Based Field‐Effect Transistor Biosensors
title_sort fabrication and functionalisation of nanocarbon‐based field‐effect transistor biosensors
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092808/
https://www.ncbi.nlm.nih.gov/pubmed/36193790
http://dx.doi.org/10.1002/cbic.202200282
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