Cargando…

An intranasal influenza virus-vectored vaccine prevents SARS-CoV-2 replication in respiratory tissues of mice and hamsters

Current available vaccines for COVID-19 are effective in reducing severe diseases and deaths caused by SARS-CoV-2 infection but less optimal in preventing infection. Next-generation vaccines which are able to induce mucosal immunity in the upper respiratory to prevent or reduce infections caused by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deng, Shaofeng, Liu, Ying, Tam, Rachel Chun-Yee, Chen, Pin, Zhang, Anna Jinxia, Mok, Bobo Wing-Yee, Long, Teng, Kukic, Anja, Zhou, Runhong, Xu, Haoran, Song, Wenjun, Chan, Jasper Fuk-Woo, To, Kelvin Kai-Wang, Chen, Zhiwei, Yuen, Kwok-Yung, Wang, Pui, Chen, Honglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092940/ https://www.ncbi.nlm.nih.gov/pubmed/37045873 http://dx.doi.org/10.1038/s41467-023-37697-1

Ejemplares similares

Characterization of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein
por: Wang, Pui, et al.
Publicado: (2021)

Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction
por: Lau, Siu-Ying, et al.
Publicado: (2020)

Nasal prevention of SARS-CoV-2 infection by intranasal influenza-based boost vaccination in mouse models
por: Zhou, Runhong, et al.
Publicado: (2021)

Low dose inocula of SARS-CoV-2 Alpha variant transmits more efficiently than earlier variants in hamsters
por: Mok, Bobo Wing-Yee, et al.
Publicado: (2021)

A broadly neutralizing antibody protects Syrian hamsters against SARS-CoV-2 Omicron challenge
por: Zhou, Biao, et al.
Publicado: (2022)

An NS-segment exonic splicing enhancer regulates influenza A virus replication in mammalian cells
por: Huang, Xiaofeng, et al.
Publicado: (2017)

Generation of DelNS1 Influenza Viruses: a Strategy for Optimizing Live Attenuated Influenza Vaccines
por: Wang, Pui, et al.
Publicado: (2019)

Intranasal administration of a single dose of a candidate live attenuated vaccine derived from an NSP16-deficient SARS-CoV-2 strain confers sterilizing immunity in animals
por: Ye, Zi-Wei, et al.
Publicado: (2022)

An A14U Substitution in the 3′ Noncoding Region of the M Segment of Viral RNA Supports Replication of Influenza Virus with an NS1 Deletion by Modulating Alternative Splicing of M Segment mRNAs
por: Zheng, Min, et al.
Publicado: (2015)

Coinfection by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza A(H1N1)pdm09 Virus Enhances the Severity of Pneumonia in Golden Syrian Hamsters
por: Zhang, Anna Jinxia, et al.
Publicado: (2020)

Intranasal infection by SARS-CoV-2 Omicron variants can induce inflammatory brain damage in newly weaned hamsters
por: Li, Can, et al.
Publicado: (2023)

Cross-species transmission and emergence of novel viruses from birds
por: Chan, Jasper Fuk-Woo, et al.
Publicado: (2015)

A Phase 1, Randomized, Double-Blinded, Placebo-Controlled and Dose-Escalation Study to Evaluate the Safety and Immunogenicity of the Intranasal DelNS1-nCoV-RBD LAIV for COVID-19 in Healthy Adults
por: Zhang, Ruiqi, et al.
Publicado: (2023)

The PB2 Polymerase Host Adaptation Substitutions Prime Avian Indonesia Sub Clade 2.1 H5N1 Viruses for Infecting Humans
por: Wang, Pui, et al.
Publicado: (2019)

The K526R substitution in viral protein PB2 enhances the effects of E627K on influenza virus replication
por: Song, Wenjun, et al.
Publicado: (2014)

Intranasal Boosting with Spike Fc-RBD of Wild-Type SARS-CoV-2 Induces Neutralizing Antibodies against Omicron Subvariants and Reduces Viral Load in the Nasal Turbinate of Mice
por: Cai, Jian-Piao, et al.
Publicado: (2023)

Cellular 5′-3′ mRNA Exoribonuclease XRN1 Inhibits Interferon Beta Activation and Facilitates Influenza A Virus Replication
por: Liu, Yen-Chin, et al.
Publicado: (2021)

A trifunctional peptide broadly inhibits SARS-CoV-2 Delta and Omicron variants in hamsters
por: Zhao, Hanjun, et al.
Publicado: (2022)

Cross-variant protection against SARS-CoV-2 infection in hamsters immunized with monovalent and bivalent inactivated vaccines
por: Ye, Zi-Wei, et al.
Publicado: (2022)

Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters
por: Lee, Andrew Chak-Yiu, et al.
Publicado: (2020)

Pathogenicity of SARS-CoV-2 Omicron BA.1.1 in hamsters
por: Chan, Jasper Fuk-Woo, et al.
Publicado: (2022)

Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infection
por: Ye, Zi-Wei, et al.
Publicado: (2021)

SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters
por: Qiao, Wei, et al.
Publicado: (2022)

Host genes and influenza pathogenesis in humans: an emerging paradigm
por: To, Kelvin Kai-Wang, et al.
Publicado: (2015)

The emergence of influenza A H7N9 in human beings 16 years after influenza A H5N1: a tale of two cities
por: To, Kelvin KW, et al.
Publicado: (2013)

Author Correction: SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters
por: Qiao, Wei, et al.
Publicado: (2022)

SARS-CoV-2 hijacks neutralizing dimeric IgA for nasal infection and injury in Syrian hamsters(1)
por: Zhou, Biao, et al.
Publicado: (2023)

Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system
por: Yeung, Man Lung, et al.
Publicado: (2021)

A novel linker-immunodominant site (LIS) vaccine targeting the SARS-CoV-2 spike protein protects against severe COVID-19 in Syrian hamsters
por: Zhang, Bao-Zhong, et al.
Publicado: (2021)

Interspecies transmission and emergence of novel viruses: lessons from bats and birds
por: Chan, Jasper Fuk-Woo, et al.
Publicado: (2013)

Epstein-Barr Virus BART Long Non-coding RNAs Function as Epigenetic Modulators in Nasopharyngeal Carcinoma
por: Verhoeven, Rob J. A., et al.
Publicado: (2019)

Clinical Performance of the Luminex NxTAG CoV Extended Panel for SARS-CoV-2 Detection in Nasopharyngeal Specimens from COVID-19 Patients in Hong Kong
por: Chen, Jonathan Hon-Kwan, et al.
Publicado: (2020)

Whipple’s disease presenting as weight gain and constipation in a Chinese woman
por: Ye, Haiyan, et al.
Publicado: (2023)

Pathogenesis and Host Response in Syrian Hamsters following Intranasal Infection with Andes Virus
por: Safronetz, David, et al.
Publicado: (2011)

Effect of Prophylactic Use of Intranasal Oil Formulations in the Hamster Model of COVID-19
por: Rizvi, Zaigham Abbas, et al.
Publicado: (2021)

Cross-reactive antibodies in convalescent SARS patients' sera against the emerging novel human coronavirus EMC (2012) by both immunofluorescent and neutralizing antibody tests
por: Chan, Kwok-Hung, et al.
Publicado: (2013)

Fatal anti-aquaporin-4 seropositive neuromyelitis optica spectrum disorder in tuberculosis
por: Sridhar, Siddharth, et al.
Publicado: (2014)

High neutralizing antibody titer in intensive care unit patients with COVID-19
por: Liu, Li, et al.
Publicado: (2020)

Intranasal influenza-vectored COVID-19 vaccine restrains the SARS-CoV-2 inflammatory response in hamsters
por: Zhang, Liang, et al.
Publicado: (2023)

Absence of Vaccine-enhanced Disease With Unexpected Positive Protection Against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by Inactivated Vaccine Given Within 3 Days of Virus Challenge in Syrian Hamster Model
por: Li, Can, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_3v6eaj321eldlgn19p6qurst2o