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Spinal Schwannomatosis Mimicking Metastatic Extramedullary Spinal Tumor

Intradural extramedullary (IDEM) tumors are the most commonly observed intraspinal tumors, comprising over 60% of tumors found within the spinal canal, and the vast majority of these lesions are benign lesions. IDEM metastases are rare, but if they occur, they commonly manifest as leptomeningeal dis...

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Autores principales: Nurdillah, Idris, Rizuana, Iqbal Hussain, Syazarina, Sharis Osman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092950/
https://www.ncbi.nlm.nih.gov/pubmed/37046472
http://dx.doi.org/10.3390/diagnostics13071254
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author Nurdillah, Idris
Rizuana, Iqbal Hussain
Syazarina, Sharis Osman
author_facet Nurdillah, Idris
Rizuana, Iqbal Hussain
Syazarina, Sharis Osman
author_sort Nurdillah, Idris
collection PubMed
description Intradural extramedullary (IDEM) tumors are the most commonly observed intraspinal tumors, comprising over 60% of tumors found within the spinal canal, and the vast majority of these lesions are benign lesions. IDEM metastases are rare, but if they occur, they commonly manifest as leptomeningeal disease, secondary to drop lesions from intracranial metastases from adenocarcinomas of the lung, prostate cancer, breast cancer, melanoma, or rarely, as a result of lymphomas. The purely non-neurogenic origin of IDEM metastases is rare. Herein, we describe a patient with a previous history of treated colon cancer who presented with a progressive neurological deficit and whose imaging revealed multiple intradural, extramedullary and osseous lesions at the cervical and thoracolumbar spines. With the previous known primary and multiplicity of the lesions, an initial diagnosis of spinal metastasis was made, But it was proven to be schwannoma on histology. We emphasize the diagnostic dilemma in this case and the importance of detecting subtle imaging findings, which may be helpful to differentiate between metastatic disease and a second primary tumor.
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spelling pubmed-100929502023-04-13 Spinal Schwannomatosis Mimicking Metastatic Extramedullary Spinal Tumor Nurdillah, Idris Rizuana, Iqbal Hussain Syazarina, Sharis Osman Diagnostics (Basel) Interesting Images Intradural extramedullary (IDEM) tumors are the most commonly observed intraspinal tumors, comprising over 60% of tumors found within the spinal canal, and the vast majority of these lesions are benign lesions. IDEM metastases are rare, but if they occur, they commonly manifest as leptomeningeal disease, secondary to drop lesions from intracranial metastases from adenocarcinomas of the lung, prostate cancer, breast cancer, melanoma, or rarely, as a result of lymphomas. The purely non-neurogenic origin of IDEM metastases is rare. Herein, we describe a patient with a previous history of treated colon cancer who presented with a progressive neurological deficit and whose imaging revealed multiple intradural, extramedullary and osseous lesions at the cervical and thoracolumbar spines. With the previous known primary and multiplicity of the lesions, an initial diagnosis of spinal metastasis was made, But it was proven to be schwannoma on histology. We emphasize the diagnostic dilemma in this case and the importance of detecting subtle imaging findings, which may be helpful to differentiate between metastatic disease and a second primary tumor. MDPI 2023-03-27 /pmc/articles/PMC10092950/ /pubmed/37046472 http://dx.doi.org/10.3390/diagnostics13071254 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Interesting Images
Nurdillah, Idris
Rizuana, Iqbal Hussain
Syazarina, Sharis Osman
Spinal Schwannomatosis Mimicking Metastatic Extramedullary Spinal Tumor
title Spinal Schwannomatosis Mimicking Metastatic Extramedullary Spinal Tumor
title_full Spinal Schwannomatosis Mimicking Metastatic Extramedullary Spinal Tumor
title_fullStr Spinal Schwannomatosis Mimicking Metastatic Extramedullary Spinal Tumor
title_full_unstemmed Spinal Schwannomatosis Mimicking Metastatic Extramedullary Spinal Tumor
title_short Spinal Schwannomatosis Mimicking Metastatic Extramedullary Spinal Tumor
title_sort spinal schwannomatosis mimicking metastatic extramedullary spinal tumor
topic Interesting Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092950/
https://www.ncbi.nlm.nih.gov/pubmed/37046472
http://dx.doi.org/10.3390/diagnostics13071254
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