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Accurate Detection of Alzheimer’s Disease Using Lightweight Deep Learning Model on MRI Data

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by cognitive impairment and aberrant protein deposition in the brain. Therefore, the early detection of AD is crucial for the development of effective treatments and interventions, as the disease is more responsive to treatment i...

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Autores principales: El-Latif, Ahmed A. Abd, Chelloug, Samia Allaoua, Alabdulhafith, Maali, Hammad, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093003/
https://www.ncbi.nlm.nih.gov/pubmed/37046434
http://dx.doi.org/10.3390/diagnostics13071216
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author El-Latif, Ahmed A. Abd
Chelloug, Samia Allaoua
Alabdulhafith, Maali
Hammad, Mohamed
author_facet El-Latif, Ahmed A. Abd
Chelloug, Samia Allaoua
Alabdulhafith, Maali
Hammad, Mohamed
author_sort El-Latif, Ahmed A. Abd
collection PubMed
description Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by cognitive impairment and aberrant protein deposition in the brain. Therefore, the early detection of AD is crucial for the development of effective treatments and interventions, as the disease is more responsive to treatment in its early stages. It is worth mentioning that deep learning techniques have been successfully applied in recent years to a wide range of medical imaging tasks, including the detection of AD. These techniques have the ability to automatically learn and extract features from large datasets, making them well suited for the analysis of complex medical images. In this paper, we propose an improved lightweight deep learning model for the accurate detection of AD from magnetic resonance imaging (MRI) images. Our proposed model achieves high detection performance without the need for deeper layers and eliminates the use of traditional methods such as feature extraction and classification by combining them all into one stage. Furthermore, our proposed method consists of only seven layers, making the system less complex than other previous deep models and less time-consuming to process. We evaluate our proposed model using a publicly available Kaggle dataset, which contains a large number of records in a small dataset size of only 36 Megabytes. Our model achieved an overall accuracy of 99.22% for binary classification and 95.93% for multi-classification tasks, which outperformed other previous models. Our study is the first to combine all methods used in the publicly available Kaggle dataset for AD detection, enabling researchers to work on a dataset with new challenges. Our findings show the effectiveness of our lightweight deep learning framework to achieve high accuracy in the classification of AD.
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spelling pubmed-100930032023-04-13 Accurate Detection of Alzheimer’s Disease Using Lightweight Deep Learning Model on MRI Data El-Latif, Ahmed A. Abd Chelloug, Samia Allaoua Alabdulhafith, Maali Hammad, Mohamed Diagnostics (Basel) Article Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by cognitive impairment and aberrant protein deposition in the brain. Therefore, the early detection of AD is crucial for the development of effective treatments and interventions, as the disease is more responsive to treatment in its early stages. It is worth mentioning that deep learning techniques have been successfully applied in recent years to a wide range of medical imaging tasks, including the detection of AD. These techniques have the ability to automatically learn and extract features from large datasets, making them well suited for the analysis of complex medical images. In this paper, we propose an improved lightweight deep learning model for the accurate detection of AD from magnetic resonance imaging (MRI) images. Our proposed model achieves high detection performance without the need for deeper layers and eliminates the use of traditional methods such as feature extraction and classification by combining them all into one stage. Furthermore, our proposed method consists of only seven layers, making the system less complex than other previous deep models and less time-consuming to process. We evaluate our proposed model using a publicly available Kaggle dataset, which contains a large number of records in a small dataset size of only 36 Megabytes. Our model achieved an overall accuracy of 99.22% for binary classification and 95.93% for multi-classification tasks, which outperformed other previous models. Our study is the first to combine all methods used in the publicly available Kaggle dataset for AD detection, enabling researchers to work on a dataset with new challenges. Our findings show the effectiveness of our lightweight deep learning framework to achieve high accuracy in the classification of AD. MDPI 2023-03-23 /pmc/articles/PMC10093003/ /pubmed/37046434 http://dx.doi.org/10.3390/diagnostics13071216 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
El-Latif, Ahmed A. Abd
Chelloug, Samia Allaoua
Alabdulhafith, Maali
Hammad, Mohamed
Accurate Detection of Alzheimer’s Disease Using Lightweight Deep Learning Model on MRI Data
title Accurate Detection of Alzheimer’s Disease Using Lightweight Deep Learning Model on MRI Data
title_full Accurate Detection of Alzheimer’s Disease Using Lightweight Deep Learning Model on MRI Data
title_fullStr Accurate Detection of Alzheimer’s Disease Using Lightweight Deep Learning Model on MRI Data
title_full_unstemmed Accurate Detection of Alzheimer’s Disease Using Lightweight Deep Learning Model on MRI Data
title_short Accurate Detection of Alzheimer’s Disease Using Lightweight Deep Learning Model on MRI Data
title_sort accurate detection of alzheimer’s disease using lightweight deep learning model on mri data
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093003/
https://www.ncbi.nlm.nih.gov/pubmed/37046434
http://dx.doi.org/10.3390/diagnostics13071216
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