Cargando…

High Levels of FGF11 Correlate with Poor Survival in Patients with Human Papillomavirus (HPV)-Positive Oropharyngeal Squamous Cell Carcinoma

SIMPLE SUMMARY: To better identify patients with human papillomavirus (HPV)-positive oropharyngeal cancer (OPSCC) and a poor prognosis after treatment, we compared the gene expression in tumours from patients with a poor or a favourable prognosis in a case-control setting. The results were thereafte...

Descripción completa

Detalles Bibliográficos
Autores principales:	de Flon, Caroline Haglund, Haeggblom, Linnea, Holzhauser, Stefan, Kostopoulou, Ourania N., Zupancic, Mark, Dalianis, Tina, Munck-Wikland, Eva, Marklund, Linda, Näsman, Anders
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093012/ https://www.ncbi.nlm.nih.gov/pubmed/37046615 http://dx.doi.org/10.3390/cancers15071954

Ejemplares similares

Time to change perspectives on HPV in oropharyngeal cancer. A systematic review of HPV prevalence per oropharyngeal sub-site the last 3 years
por: Haeggblom, Linnea, et al.
Publicado: (2017)

Prevalence of human papillomavirus and survival in oropharyngeal cancer other than tonsil or base of tongue cancer
por: Marklund, Linda, et al.
Publicado: (2012)

Psoriasin expression is associated with survival in patients with human papillomavirus-positive base of tongue squamous cell carcinoma
por: Zupancic, Mark, et al.
Publicado: (2021)

Absent/weak CD44 intensity and positive human papillomavirus (HPV) status in oropharyngeal squamous cell carcinoma indicates a very high survival
por: Näsman, Anders, et al.
Publicado: (2013)

Protein Expression in Tonsillar and Base of Tongue Cancer and in Relation to Human Papillomavirus (HPV) and Clinical Outcome
por: Ramqvist, Torbjörn, et al.
Publicado: (2018)

Long-Term Survival and Recurrence in Oropharyngeal Squamous Cell Carcinoma in Relation to Subsites, HPV, and p16-Status
por: Wendt, Malin, et al.
Publicado: (2021)

Prognostic Markers and Driver Genes and Options for Targeted Therapy in Human-Papillomavirus-Positive Tonsillar and Base-of-Tongue Squamous Cell Carcinoma
por: Näsman, Anders, et al.
Publicado: (2021)

Correlation of LMP10 Expression and Clinical Outcome in Human Papillomavirus (HPV) Positive and HPV-Negative Tonsillar and Base of Tongue Cancer
por: Tertipis, Nikolaos, et al.
Publicado: (2014)

Targeted Therapy With PI3K and FGFR Inhibitors on Human Papillomavirus Positive and Negative Tonsillar and Base of Tongue Cancer Lines With and Without Corresponding Mutations
por: Holzhauser, Stefan, et al.
Publicado: (2021)

Tumor Infiltrating CD8(+) and Foxp3(+) Lymphocytes Correlate to Clinical Outcome and Human Papillomavirus (HPV) Status in Tonsillar Cancer
por: Näsman, Anders, et al.
Publicado: (2012)

HLA Class I and II Expression in Oropharyngeal Squamous Cell Carcinoma in Relation to Tumor HPV Status and Clinical Outcome
por: Näsman, Anders, et al.
Publicado: (2013)

Analysis of Human Papillomavirus (HPV) and Polyomaviruses (HPyVs) in Adenoid Cystic Carcinoma (AdCC) of the Head and Neck Region Reveals Three HPV-Positive Cases with Adenoid Cystic-like Features
por: Zupancic, Mark, et al.
Publicado: (2022)

Tumour inflammation signature and expression of S100A12 and HLA class I improve survival in HPV-negative hypopharyngeal cancer
por: Mints, Michael, et al.
Publicado: (2021)

Targeted sequencing of tonsillar and base of tongue cancer and human papillomavirus positive unknown primary of the head and neck reveals prognostic effects of mutated FGFR3
por: Bersani, Cinzia, et al.
Publicado: (2017)

Post-Treatment Neck Dissection of Tonsillar and Base of Tongue Squamous Cell Carcinoma in the Era of PET-CT, HPV, and p16
por: Landin, David, et al.
Publicado: (2022)

Targeted Therapy with PI3K, PARP, and WEE1 Inhibitors and Radiotherapy in HPV Positive and Negative Tonsillar Squamous Cell Carcinoma Cell Lines Reveals Synergy while Effects with APR-246 Are Limited
por: Byskata, Karin, et al.
Publicado: (2022)

Human papillomavirus and p53 expression in cancer of unknown primary in the head and neck region in relation to clinical outcome
por: Sivars, Lars, et al.
Publicado: (2014)

Targeted Therapy of HPV Positive and Negative Tonsillar Squamous Cell Carcinoma Cell Lines Reveals Synergy between CDK4/6, PI3K and Sometimes FGFR Inhibitors, but Rarely between PARP and WEE1 Inhibitors
por: Kostopoulou, Ourania N., et al.
Publicado: (2022)

Whole-Exome Sequencing of HPV Positive Tonsillar and Base of Tongue Squamous Cell Carcinomas Reveals a Global Mutational Pattern along with Relapse-Specific Somatic Variants
por: Ährlund-Richter, Andreas, et al.
Publicado: (2021)

Human papillomavirus and survival of patients per histological subsite of tonsillar squamous cell carcinoma
por: Haeggblom, Linnea, et al.
Publicado: (2018)

Reduced Expression of the Antigen Processing Machinery Components TAP2, LMP2, and LMP7 in Tonsillar and Base of Tongue Cancer and Implications for Clinical Outcome()
por: Tertipis, Nikolaos, et al.
Publicado: (2015)

Oropharyngeal Cancer Epidemic and Human Papillomavirus
por: Ramqvist, Torbjörn, et al.
Publicado: (2010)

Special Issue “HPV in the Head and Neck Region”
por: Dalianis, Tina, et al.
Publicado: (2021)

Combination of PARP and WEE1 inhibitors in vitro: Potential for use in the treatment of SHH medulloblastoma
por: Lukoseviciute, Monika, et al.
Publicado: (2023)

Development and external validation of nomograms in oropharyngeal cancer patients with known HPV-DNA status: a European Multicentre Study (OroGrams)
por: Grønhøj, Christian, et al.
Publicado: (2018)

Human Papillomavirus (HPV) 16 E6 Variants in Tonsillar Cancer in Comparison to Those in Cervical Cancer in Stockholm, Sweden
por: Du, Juan, et al.
Publicado: (2012)

Expression of LRIG1 is associated with good prognosis and human papillomavirus status in oropharyngeal cancer
por: Lindquist, D, et al.
Publicado: (2014)

Changes in Cervical Human Papillomavirus (HPV) Prevalence at a Youth Clinic in Stockholm, Sweden, a Decade After the Introduction of the HPV Vaccine
por: Ährlund-Richter, Andreas, et al.
Publicado: (2019)

Efficacy of combined targeted therapy with PI3K and CDK4/6 or PARP and WEE1 inhibitors in neuroblastoma cell lines
por: Lukoseviciute, Monika, et al.
Publicado: (2023)

Special Issue “HPV in the Head and Neck Region 2.0”
por: Dalianis, Tina, et al.
Publicado: (2023)

Human papilloma virus (HPV) prevalence upon HPV vaccination in Swedish youth: a review based on our findings 2008–2018, and perspectives on cancer prevention
por: Du, Juan, et al.
Publicado: (2020)

No evidence for human papillomavirus having a causal role in salivary gland tumors
por: Haeggblom, Linnea, et al.
Publicado: (2018)

Differences in gene expression between high‐grade dysplasia and invasive HPV(+) and HPV(−) tonsillar and base of tongue cancer
por: Haeggblom, Linnea, et al.
Publicado: (2019)

Human papillomavirus and oropharyngeal cancer, the epidemics, and significance of additional clinical biomarkers for prediction of response to therapy
por: DALIANIS, TINA
Publicado: (2014)

Prevalence of Human Papillomavirus (HPV) in Oesophageal Squamous Cell Carcinoma in Relation to Anatomical Site of the Tumour
por: Löfdahl, Hedvig E., et al.
Publicado: (2012)

Adenoid Cystic Carcinoma (AdCC): A Clinical Survey of a Large Patient Cohort
por: Zupancic, Mark, et al.
Publicado: (2023)

Impact of HPV in Oropharyngeal Cancer
por: Marklund, Linda, et al.
Publicado: (2011)

Targeting PI3K, FGFR, CDK4/6 Signaling Pathways Together With Cytostatics and Radiotherapy in Two Medulloblastoma Cell Lines
por: Lukoseviciute, Monika, et al.
Publicado: (2021)

Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma—An Even Broader Tumor Entity?
por: Zupancic, Mark, et al.
Publicado: (2021)

Effects of PI3K and FGFR inhibitors alone and in combination, and with/without cytostatics in childhood neuroblastoma cell lines
por: Holzhauser, Stefan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9havfcisargti7dihnmhuvfou3