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Ethanol Exposure to Ethanol-Oxidizing HEPG2 Cells Induces Intracellular Protein Aggregation

Background: Aggresomes are collections of intracellular protein aggregates. In liver cells of patients with alcoholic hepatitis, aggresomes appear histologically as cellular inclusions known as Mallory–Denk (M–D) bodies. The proteasome is a multicatalytic intracellular protease that catalyzes the de...

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Detalles Bibliográficos
Autores principales: Thomes, Paul G., Rensch, Gage, Casey, Carol A., Donohue, Terrence M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093015/
https://www.ncbi.nlm.nih.gov/pubmed/37048086
http://dx.doi.org/10.3390/cells12071013